High-efficiency full-length cDNA cloning.Carninci P., Hayashizaki Y.Cited forNUCLEOTIDE SEQUENCEStrainC57BL/6JTissueDiencephalon, KidneyCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCMethods Enzymol 303:19-44 (1999)Cited in99+Mapped to15
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCEStrainC57BL/6JTissueDiencephalon, KidneyCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCGenome Res. 10:1617-1630 (2000)Cited in199+Mapped to10
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K.[...], Togawa Y.View abstractCited forNUCLEOTIDE SEQUENCEStrainC57BL/6JTissueDiencephalon, KidneyCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCGenome Res 10:1757-1771 (2000)Cited in99+
Functional annotation of a full-length mouse cDNA collection.Kawai J., Shinagawa A., Shibata K., Yoshino M., Itoh M., Ishii Y., Arakawa T., Hara A., Fukunishi Y.[...], Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCEStrainC57BL/6JTissueDiencephalon, KidneyCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCNature 409:685-690 (2001)Cited in399+Mapped to99+
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.Okazaki Y., Furuno M., Kasukawa T., Adachi J., Bono H., Kondo S., Nikaido I., Osato N., Saito R.[...], Hayashizaki Y.View abstractCited forNUCLEOTIDE SEQUENCEStrainC57BL/6JTissueDiencephalon, KidneyCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCNature 420:563-573 (2002)Cited in699+Mapped to99+
No title available.Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K.[...], Hayashizaki Y.Cited forNUCLEOTIDE SEQUENCEStrainC57BL/6JTissueDiencephalon, KidneyCategorySequencesSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to EMBL/GenBank/DDBJ databases (APR-2004)Cited in99+
The Transcriptional Landscape of the Mammalian Genome.The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)Cited forNUCLEOTIDE SEQUENCEStrainC57BL/6JTissueDiencephalon, KidneyCategorySequencesSourceUniProtKB unreviewed (TrEMBL)Science 309:1559-1563 (2005)Cited in199+
Antisense transcription in the mammalian transcriptome.FANTOM ConsortiumKatayama S., Tomaru Y., Kasukawa T., Waki K., Nakanishi M., Nakamura M., Nishida H., Yap C.C., Suzuki M.[...], Wahlestedt C.View abstractCited forNUCLEOTIDE SEQUENCEStrainC57BL/6JTissueDiencephalon, KidneyCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCScience 309:1564-1566 (2005)Cited in99+
An essential role for Cmtr2 in mammalian embryonic development.Yermalovich A.V., Mohsenin Z., Cowdin M., Giotti B., Gupta A., Feng A., Golomb L., Wheeler D.B., Xu K.[...], Meyerson M.View abstractSourceMGI: 1918836PubMedEurope PMCDev Biol 516:47-58 (2024)Mapped to38
Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1- mediated immunity in the liver.Gan W.L., Ren X., Ng V.H.E., Ng L., Song Y., Tano V., Han J., An O., Xie J.[...], Chen L.View abstractSourceMGI: 1918836PubMedEurope PMCCell Rep 43:114400-114400 (2024)Mapped to14
The IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner.Stock A.J., Gonzalez Paredes P., de Almeida L.P., Kosanke S.D., Chetlur S., Budde H., Wakenight P., Zwingman T.A., Rosen A.B.I.[...], Gorman J.A.View abstractAnnotationThe IFIH1-A946T risk variant promotes diabetes in a sex-dependent manner.CategoryFunctionSourceGeneRif: 71586PubMedEurope PMCFront Immunol 15:1349601-1349601 (2024)Mapped to7
Aberrant RNA sensing in regulatory T cells causes systemic autoimmunity.Luca D., Lee S., Hirota K., Okabe Y., Uehori J., Izawa K., Lanz A.L., Schutte V., Sivri B.[...], Kato H.View abstractCategoryFunctionSourceMGI: 1918836PubMedEurope PMCSci Adv 10:eadk0820-eadk0820 (2024)Mapped to32
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractCategoryFunctionSourceMGI: 1918836PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Disrupted RNA editing in beta cells mimics early-stage type 1 diabetes.Knebel U.E., Peleg S., Dai C., Cohen-Fultheim R., Jonsson S., Poznyak K., Israeli M., Zamashanski L., Glaser B.[...], Dor Y.View abstractCategoryFunctionSourceMGI: 1918836PubMedEurope PMCCell Metab 36:48-61.e6 (2024)Mapped to14
ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation.Hu S.B., Heraud-Farlow J., Sun T., Liang Z., Goradia A., Taylor S., Walkley C.R., Li J.B.View abstractAnnotationADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation.CategoryFunctionSourceGeneRif: 71586, MGI: 1918836PubMedEurope PMCMol Cell 83:3869-3884.e7 (2023)Mapped to20
MDA5 Enhances Invasive Candida albicans Infection by Regulating Macrophage Apoptosis and Phagocytosis/Killing Functions.Chen Y., Jiang Q., Qing F., Xue J., Xiao Q., He W., Sui L., Liu Z.View abstractAnnotationMDA5 Enhances Invasive Candida albicans Infection by Regulating Macrophage Apoptosis and Phagocytosis/Killing Functions.CategoryFunctionSourceGeneRif: 71586PubMedEurope PMCInflammation 47:191-208 (2024)Mapped to11
MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival.Bullen C.K., Singh A.K., Krug S., Lun S., Thakur P., Srikrishna G., Bishai W.R.View abstractAnnotationMDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival.CategoryFunctionSourceGeneRif: 71586PubMedEurope PMCJCI Insight 8:e166242-e166242 (2023)Mapped to7
Long noncoding RNA 1392 regulates MDA5 by interaction with ELAVL1 to inhibit coxsackievirus B5 infection.Li J., Li J., Teng P., Yang F., Zhang J., Sun B., Chen W.View abstractAnnotationLong noncoding RNA 1392 regulates MDA5 by interaction with ELAVL1 to inhibit coxsackievirus B5 infection.CategoryFunctionSourceGeneRif: 71586PubMedEurope PMCVirol Sin 38:699-708 (2023)Mapped to14
ADAR1 Zalpha domain P195A mutation activates the MDA5-dependent RNA- sensing signaling pathway in brain without decreasing overall RNA editing.Guo X., Liu S., Sheng Y., Zenati M., Billiar T., Herbert A., Wang Q.View abstractSourceMGI: 1918836PubMedEurope PMCCell Rep 42:112733-112733 (2023)Mapped to16
The phenotype of the most common human ADAR1p150 Zalpha mutation P193A in mice is partially penetrant.Liang Z., Chalk A.M., Taylor S., Goradia A., Heraud-Farlow J.E., Walkley C.R.View abstractCategoryFunctionSourceMGI: 1918836PubMedEurope PMCEMBO Rep 24:e55835-e55835 (2023)Mapped to14
Theilovirus 3C Protease Cleaves the C-Terminal Domain of the Innate Immune RNA Sensor, Melanoma Differentiation-Associated Gene 5, and Impairs Double- Stranded RNA-Mediated IFN Response.Miyamoto M., Himeda T., Ishihara K., Okuwa T., Kobayashi D., Nameta M., Karasawa Y., Chunhaphinyokul B., Yoshida Y.[...], Komuro A.View abstractAnnotationTheilovirus 3C Protease Cleaves the C-Terminal Domain of the Innate Immune RNA Sensor Melanoma Differentiation-Associated Gene 5 and Impairs Double-Stranded RNA-Mediated IFN Response.CategoryFunctionSourceGeneRif: 71586PubMedEurope PMCJ Immunol 210:335-347 (2023)Mapped to7
MDA5-dependent responses contribute to autoimmune diabetes progression and hindrance.Blum S.I., Taylor J.P., Barra J.M., Burg A.R., Shang Q., Qiu S., Shechter O., Hayes A.R., Green T.J.[...], Tse H.M.View abstractCategoryFunctionSourceMGI: 1918836PubMedEurope PMCJCI Insight 8:e157929-e157929 (2023)Mapped to7
Adenosine deaminase acting on RNA-1 is essential for early B lymphopoiesis.Chen W., Li Y., Ruan G.X., Huang H., Zhang R., Wang J., Ouyang Y., Li Y., Xu S., Ou X.View abstractCategoryFunctionSourceMGI: 1918836PubMedEurope PMCCell Rep 41:111687-111687 (2022)Mapped to26
A Study on MDA5 Signaling in Splenic B Cells from an Imiquimod-Induced Lupus Mouse Model with Proteomics.Su Y.J., Li F.A., Sheu J.J., Li S.C., Weng S.W., Shen F.C., Chang Y.H., Chen H.Y., Liou C.W.[...], Wang P.W.View abstractAnnotationA Study on MDA5 Signaling in Splenic B Cells from an Imiquimod-Induced Lupus Mouse Model with Proteomics.CategoriesFunction, InteractionSourceGeneRif: 71586PubMedEurope PMCCells 11:3350-3350 (2022)Mapped to7
Attenuation of regulatory T cell function by type I IFN signaling in an MDA5 gain-of-function mutant mouse model.Lee S., Hirota K., Schuette V., Fujita T., Kato H.View abstractAnnotationAttenuation of regulatory T cell function by type I IFN signaling in an MDA5 gain-of-function mutant mouse model.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 71586, MGI: 1918836PubMedEurope PMCBiochem Biophys Res Commun 629:171-175 (2022)Mapped to7