Q3TG86 · Q3TG86_MOUSE

  • Protein
    steroid 11beta-monooxygenase
  • Gene
    Cyp11b1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

Catalytic activity

Cofactor

heme (UniProtKB | Rhea| CHEBI:30413 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site38221-hydroxyprogesterone (UniProtKB | ChEBI)
Binding site448Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentmitochondrial inner membrane
Cellular Componentmitochondrion
Molecular Functioncorticosterone 18-monooxygenase activity
Molecular Functionheme binding
Molecular Functioniron ion binding
Molecular Functionsteroid 11-beta-monooxygenase activity
Molecular Functionsteroid binding
Biological Processaldosterone biosynthetic process
Biological Processcellular response to peptide hormone stimulus
Biological Processcholesterol metabolic process
Biological Processcortisol biosynthetic process
Biological Processcortisol metabolic process
Biological Processglucocorticoid biosynthetic process
Biological Processsteroid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    steroid 11beta-monooxygenase
  • EC number

Gene names

    • Name
      Cyp11b1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q3TG86

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the cytochrome P450 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    501
  • Mass (Da)
    57,747
  • Last updated
    2005-10-11 v1
  • Checksum
    9E1F5386BF18FBA1
MTMALRVTTDVWLARPWQCLHRTRALGTTATLAPKTLQPFEAIPQYSRNKWLKMIQILREQGQENLHLEMHQVFRELGPIFRHSVGKTQIVFVTLPEDVEKLYQVESTHPCRMPLESWIVHRELRGLGRGVFLLNGPEWYFNRLQLNPNVLSPKAVQKFVPLVDGIARDFVDNLKKKMLESVHGSFSMDFQSSVFNYTIEASHFVLFGERLGLIGRDLSPDSLKFLHTLHSMFKTTTQLLYLPRSLTRWTSTRVWKENLESWDFISEYVTKCIKNVYRELAEGRPQSWSVTAELVAERTLSMDAIQANSMELIAGSTDTTSTPLVMTFFELARNPDVQQALRQESLAAEASIAANPQKAMSDLPLLRAALKETLRLYPVGTFLERILSSDLVLQNYHVPAGTVLNVNLYSMGRNPAVFPRPERYMPQRWLERKRSFKHLAFGFGVRQCLGRRLAEAEMMLLLHHVLKSFHVETQEKEDVRMAYRFVLMPSSSPLLTFRPVN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC139248
EMBL· GenBank· DDBJ
AAI39249.1
EMBL· GenBank· DDBJ
mRNA
BC139250
EMBL· GenBank· DDBJ
AAI39251.1
EMBL· GenBank· DDBJ
mRNA
AK168839
EMBL· GenBank· DDBJ
BAE40662.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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