Q3TCF3 · Q3TCF3_MOUSE

  • Protein
    L-selectin
  • Gene
    Sell
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Features

Showing features for binding site.

133650100150200250300
TypeIDPosition(s)Description
Binding site118Ca2+ (UniProtKB | ChEBI)
Binding site120Ca2+ (UniProtKB | ChEBI)
Binding site126Ca2+ (UniProtKB | ChEBI)
Binding site143Ca2+ (UniProtKB | ChEBI)
Binding site144Ca2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functioncarbohydrate binding
Molecular Functionmetal ion binding
Biological Processcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Biological Processleukocyte migration

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    L-selectin

Gene names

    • Name
      Sell

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • NOD
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q3TCF3

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane298-319Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-38
ChainPRO_501509743339-336L-selectin
Disulfide bond57↔155
Disulfide bond128↔147
Disulfide bond161↔205
Disulfide bond191↔218
Disulfide bond223↔267
Disulfide bond253↔280

Keywords

Expression

Gene expression databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain34-156C-type lectin
Domain159-220Sushi
Domain221-282Sushi

Sequence similarities

Belongs to the selectin/LECAM family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    336
  • Mass (Da)
    38,463
  • Last updated
    2005-10-11 v1
  • Checksum
    60FFD09756963C66
MVFPWRCEGTYWGSRNILKLWVWTLLCCDFLIHHGTHCWTYHYSEKPMNWENARKFCKQNYTDLVAIQNKREIEYLENTLPKSPYYYWIGIRKIGKMWTWVGTNKTLTKEAENWGAGEPNNKKSKEDCVEIYIKRERDSGKWNDDACHKRKAALCYTVVQCEPLEAPELGTMDCIHPLGNFSFQSKCAFNCSEGRELLGTAETQCGASGNWSSPEPICQVVQCEPLEAPELGTMDCIHPLGNFSFQSKCAFNCSEGRELLGTAETQCGASGNWSSPEPICQETNRSFSKIKEGDYNPLFIPVAVMVTAFSGLAFLIWLARRLKKGKKSQERMDDPY

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
P18337LYAM1_MOUSESell372
A0A0A6YW25A0A0A6YW25_MOUSESell100
B1B507B1B507_MOUSESell387

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK170753
EMBL· GenBank· DDBJ
BAE42004.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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