Q3TBE0 · Q3TBE0_MOUSE

  • Protein
    Rho-associated protein kinase 1
  • Gene
    Rock1
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

GO annotations

AspectTerm
Cellular Componentbleb
Cellular Componentcentriole
Cellular Componentcytoplasmic stress granule
Cellular ComponentGolgi membrane
Cellular Componentlamellipodium
Cellular Componentplasma membrane
Cellular Componentruffle
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionRho-dependent protein serine/threonine kinase activity
Molecular Functionsmall GTPase binding
Biological Processactomyosin structure organization
Biological Processcortical actin cytoskeleton organization
Biological Processembryonic morphogenesis
Biological Processmitotic cytokinesis
Biological Processregulation of cell junction assembly
Biological ProcessRho protein signal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Rho-associated protein kinase 1
  • EC number
  • Alternative names
    • Rho-associated, coiled-coil-containing protein kinase 1
    • Rho-associated, coiled-coil-containing protein kinase I
    • p160 ROCK-1

Gene names

    • Name
      Rock1

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • NOD
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q3TBE0

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Proteomic databases

Family & Domains

Features

Showing features for coiled coil, domain, region.

TypeIDPosition(s)Description
Coiled coil15-60
Coiled coil100-141
Domain111-177RhoBD
Coiled coil182-262
Domain280-479PH
Domain390-445Phorbol-ester/DAG-type
Region495-516Disordered

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    516
  • Mass (Da)
    60,232
  • Last updated
    2005-10-11 v1
  • Checksum
    5A6B4F280176040F
MRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLRKIQELQSEKETLSTQLDLAETKAESEQLARGILEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSVLTKDIEMLRKENEELNERMRTAEEEYKLKKEEEINNLKAAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQLASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKKQYVVVSSKKILFYNDEQDKEQSSPSMVLDIDKLFHVRPVTQGDVYRAETEGIPKIFQILYANEGECRKDIEVEPVQQGEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK171291
EMBL· GenBank· DDBJ
BAE42373.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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