Q3SH14 · Q3SH14_THIDA

Function

function

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site54NADP+ (UniProtKB | ChEBI)
Binding site96-97NADP+ (UniProtKB | ChEBI)
Binding site155NADP+ (UniProtKB | ChEBI)
Binding site185substrate
Binding site189substrate
Binding site223substrate
Binding site242substrate
Active site247Proton acceptor
Binding site347substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionglucose-6-phosphate dehydrogenase activity
Molecular FunctionNADP binding
Biological Processglucose metabolic process
Biological Processpentose-phosphate shunt, oxidative branch

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Glucose-6-phosphate 1-dehydrogenase
  • EC number
  • Short names
    G6PD

Gene names

    • Name
      zwf
    • Ordered locus names
      Tbd_2122

Organism names

Accessions

  • Primary accession
    Q3SH14

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain17-194Glucose-6-phosphate dehydrogenase NAD-binding
Domain196-493Glucose-6-phosphate dehydrogenase C-terminal

Sequence similarities

Belongs to the glucose-6-phosphate dehydrogenase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    496
  • Mass (Da)
    57,010
  • Last updated
    2005-10-11 v1
  • MD5 Checksum
    02B6E47EAEEC69B4885FB0F3568C329F
MTVTKDASVENMPCSFVIFGATGNLASNKLLPALYHLEAAARLAESLSIIAFSRRDWDTASWREHMREVLRDKIKGPLDTPTFDRFLARFAYHKGDLNDPHAYHALAERLPPESSCSATVFYLAIKPAEFGAVIQNLEAAGLNKPRGLNRVVIEKPFGEDLESAQTLNRLLHQHFEEQQVYRIDHFLGKETVQNLLVFRFANTLIEPLWNRNFIDHVQITVAESGGIDKRADYYDRAGALRDMLQNHLMQLMTVVAMEPPPALEADALRDEKVKVLRSVRPISKRAVHAHAVRAQYSRGSVEGQIARAYQQEDNVEDNSTTETFVAAKFYIDNWRWRGVPFYLRTGKRMPRQTQIIAIRFRQPPQQLFRETPFESVAPNWVLLSIQPEESMHMEIHVKQPGLDMGTRVMQMNASFLKTDEQTLDAYETLLLDVIEGDRSLFIRFDEVEWAWRVVDPILKNWAVEREFIPTYPAGSWGPAEANRLFDSDDQTWRNEL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000116
EMBL· GenBank· DDBJ
AAZ98075.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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