Q3KR51 · NSG2_RAT
- ProteinNeuronal vesicle trafficking-associated protein 2
- GeneNsg2
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids171 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cytoplasmic vesicle membrane | |
Cellular Component | dendrite | |
Cellular Component | early endosome | |
Cellular Component | early endosome membrane | |
Cellular Component | endosome | |
Cellular Component | glutamatergic synapse | |
Cellular Component | Golgi cis cisterna membrane | |
Cellular Component | late endosome | |
Cellular Component | lysosomal lumen | |
Cellular Component | membrane | |
Cellular Component | multivesicular body membrane | |
Cellular Component | postsynaptic density membrane | |
Cellular Component | trans-Golgi network membrane | |
Molecular Function | clathrin light chain binding | |
Biological Process | clathrin coat assembly | |
Biological Process | endosomal transport | |
Biological Process | regulation of postsynaptic membrane neurotransmitter receptor levels |
Names & Taxonomy
Protein names
- Recommended nameNeuronal vesicle trafficking-associated protein 2
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus
Accessions
- Primary accessionQ3KR51
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass type II membrane protein
Note: Endocytosed from the cell surface, thus entered into early endosomes, trafficks to late endosomes and degradates in lysosomes (PubMed:28874679).
Mainly Golgi stack, but also found in small vacuolar organelles and multivesicular bodies. Found in both stationary and motile endosomes (By similarity).
Mainly Golgi stack, but also found in small vacuolar organelles and multivesicular bodies. Found in both stationary and motile endosomes (By similarity).
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Topological domain | 1-71 | Cytoplasmic | |||
Transmembrane | 72-92 | Helical; Signal-anchor for type II membrane protein | |||
Topological domain | 93-171 | Lumenal | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000442707 | 1-171 | Neuronal vesicle trafficking-associated protein 2 | ||
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length171
- Mass (Da)18,986
- Last updated2005-11-08 v1
- MD5 ChecksumED7C8EA9D2F66F44F108D6ED36A0A5F4
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A8I6AD04 | A0A8I6AD04_RAT | Nsg2 | 92 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AABR07029218 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CH473948 EMBL· GenBank· DDBJ | EDM04026.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CH473948 EMBL· GenBank· DDBJ | EDM04027.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CH473948 EMBL· GenBank· DDBJ | EDM04028.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CH473948 EMBL· GenBank· DDBJ | EDM04029.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BC105916 EMBL· GenBank· DDBJ | AAI05917.1 EMBL· GenBank· DDBJ | mRNA |