Q3KR51 · NSG2_RAT

  • Protein
    Neuronal vesicle trafficking-associated protein 2
  • Gene
    Nsg2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasmic vesicle membrane
Cellular Componentdendrite
Cellular Componentearly endosome
Cellular Componentearly endosome membrane
Cellular Componentendosome
Cellular Componentglutamatergic synapse
Cellular ComponentGolgi cis cisterna membrane
Cellular Componentlate endosome
Cellular Componentlysosomal lumen
Cellular Componentmembrane
Cellular Componentmultivesicular body membrane
Cellular Componentpostsynaptic density membrane
Cellular Componenttrans-Golgi network membrane
Molecular Functionclathrin light chain binding
Biological Processclathrin coat assembly
Biological Processendosomal transport
Biological Processregulation of postsynaptic membrane neurotransmitter receptor levels

Names & Taxonomy

Protein names

  • Recommended name
    Neuronal vesicle trafficking-associated protein 2
  • Alternative names
    • Neuron-specific protein family member 2

Gene names

    • Name
      Nsg2

Organism names

  • Taxonomic identifier
  • Strain
    • Brown Norway
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Rattus

Accessions

  • Primary accession
    Q3KR51

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Single-pass type II membrane protein
Endosome membrane
Lysosome lumen
Note: Endocytosed from the cell surface, thus entered into early endosomes, trafficks to late endosomes and degradates in lysosomes (PubMed:28874679).
Mainly Golgi stack, but also found in small vacuolar organelles and multivesicular bodies. Found in both stationary and motile endosomes (By similarity).

Features

Showing features for topological domain, transmembrane.

Type
IDPosition(s)Description
Topological domain1-71Cytoplasmic
Transmembrane72-92Helical; Signal-anchor for type II membrane protein
Topological domain93-171Lumenal

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004427071-171Neuronal vesicle trafficking-associated protein 2

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-21Disordered

Sequence similarities

Belongs to the NSG family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    171
  • Mass (Da)
    18,986
  • Last updated
    2005-11-08 v1
  • MD5 Checksum
    ED7C8EA9D2F66F44F108D6ED36A0A5F4
MVKLNGNPGEKGAKPPSVEDGFQTVPLITPLEVNHLQLSAPEKVIVKTRTEYQPEQRNKGKFRVPKIAEFTVTILVSLALAFLACIVFLVVYKAFTYDHSCPEGFVYKHKRCIPASLDAYYSSQDPSSRSRFYTVISHYSVAKQSTARAIGPWLSAAAVIHEPKPPKTQGH

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8I6AD04A0A8I6AD04_RATNsg292

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AABR07029218
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CH473948
EMBL· GenBank· DDBJ
EDM04026.1
EMBL· GenBank· DDBJ
Genomic DNA
CH473948
EMBL· GenBank· DDBJ
EDM04027.1
EMBL· GenBank· DDBJ
Genomic DNA
CH473948
EMBL· GenBank· DDBJ
EDM04028.1
EMBL· GenBank· DDBJ
Genomic DNA
CH473948
EMBL· GenBank· DDBJ
EDM04029.1
EMBL· GenBank· DDBJ
Genomic DNA
BC105916
EMBL· GenBank· DDBJ
AAI05917.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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