Q3K3G5 · SYC_STRA1
- ProteinCysteine--tRNA ligase
- GenecysS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids447 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- tRNA(Cys) + L-cysteine + ATP = L-cysteinyl-tRNA(Cys) + AMP + diphosphate
Cofactor
Note: Binds 1 zinc ion per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 28 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 211 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 236 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 240 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 271 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | cysteine-tRNA ligase activity | |
Molecular Function | zinc ion binding | |
Biological Process | cysteinyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCysteine--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillati > Bacillota > Bacilli > Lactobacillales > Streptococcaceae > Streptococcus
Accessions
- Primary accessionQ3K3G5
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000240962 | 1-447 | Cysteine--tRNA ligase | ||
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Motif | 30-40 | 'HIGH' region | |||
Motif | 268-272 | 'KMSKS' region | |||
Sequence similarities
Belongs to the class-I aminoacyl-tRNA synthetase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length447
- Mass (Da)50,788
- Last updated2005-11-08 v1
- MD5 Checksum68401528E764AA4204D882E67E5BF783
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000114 EMBL· GenBank· DDBJ | ABA45206.1 EMBL· GenBank· DDBJ | Genomic DNA |