Q3IJ73 · PNP_PSET1
- ProteinPolyribonucleotide nucleotidyltransferase
- Genepnp
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids708 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
Catalytic activity
- RNA(n+1) + phosphate = RNA(n) + a ribonucleoside 5'-diphosphate
Cofactor
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 488 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 494 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | 3'-5'-RNA exonuclease activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | polyribonucleotide nucleotidyltransferase activity | |
Molecular Function | RNA binding | |
Biological Process | mRNA catabolic process | |
Biological Process | RNA processing |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePolyribonucleotide nucleotidyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Pseudoalteromonadaceae > Pseudoalteromonas
Accessions
- Primary accessionQ3IJ73
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000329777 | 1-708 | Polyribonucleotide nucleotidyltransferase | ||
Interaction
Subunit
Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | IntAct | |
---|---|---|---|---|---|
BINARY | Q3IJ73 | rne Q3IHD2 | 2 | EBI-6412396, EBI-6412370 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 555-614 | KH | |||
Domain | 624-692 | S1 motif | |||
Sequence similarities
Belongs to the polyribonucleotide nucleotidyltransferase family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length708
- Mass (Da)75,599
- Last updated2005-11-08 v1
- ChecksumC3F49D29FA41D18A
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CR954246 EMBL· GenBank· DDBJ | CAI86079.1 EMBL· GenBank· DDBJ | Genomic DNA |