Q3IJ73 · PNP_PSET1

Function

function

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site.

170850100150200250300350400450500550600650700
TypeIDPosition(s)Description
Binding site488Mg2+ (UniProtKB | ChEBI)
Binding site494Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function3'-5'-RNA exonuclease activity
Molecular Functionmagnesium ion binding
Molecular Functionpolyribonucleotide nucleotidyltransferase activity
Molecular FunctionRNA binding
Biological ProcessmRNA catabolic process
Biological ProcessRNA processing

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Polyribonucleotide nucleotidyltransferase
  • EC number
  • Alternative names
    • Polynucleotide phosphorylase
      (PNPase
      )

Gene names

    • Name
      pnp
    • Ordered locus names
      PSHAa1001

Organism names

Accessions

  • Primary accession
    Q3IJ73

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003297771-708Polyribonucleotide nucleotidyltransferase

Interaction

Subunit

Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntAct
BINARY Q3IJ73rne Q3IHD22EBI-6412396, EBI-6412370

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain555-614KH
Domain624-692S1 motif

Sequence similarities

Belongs to the polyribonucleotide nucleotidyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    708
  • Mass (Da)
    75,599
  • Last updated
    2005-11-08 v1
  • Checksum
    C3F49D29FA41D18A
MQAIIKEFQLGQHTVTLETGAIARQADGAVLASIGDTSVLVTVVGKREAQPGQDFFPLTVNYQERMYAAGRIPGGFLKREGRPNDGETLIARLIDRPIRPLFPSGFVNEVQVIATVVSVNPEIQPDMVALIGTSAALAISGIPFSGPIGATRVGYIDGEYVLNPTLKELEESKLDLVVAGTDNAVLMVESEADVLAEDIMLGAVVYGHEQAQAIITAIKEFKAEAGKPTWDWTAPAKNVSLEEKVASIAADKVGEAYRITDKVARKEALGVAKDEVVAVLTSELAEGESLDKQEIGKIFGSLEKKIVRGRIAAGEKRIDGREPDMIRALDVMTGVLPRTHGSAIFTRGETQALVTATLGTERDSQLIDDLTGTHKNHFMLNYNFPPFCVGETGFVGSPKRREIGHGNLAKRGIAAVMPTLTEFPYSIRVVSEITESNGSSSMASVCGTSLALMNAGVPIKASVAGIAMGLVKEDDKFVVLSDILGDEDHLGDMDFKVAGTAGGITALQMDIKIEGITQEIMQIALKQAKAARLHILEVMDKAISAPSEELSQFAPRIYTMKIPQKKIAEVIGKGGATIRQLTEETGTTIEIGDDGTIKIAATDGESAANAISRIEQLTAELEVGTIYEGKVVRIVDFGAFVNILPGKDGLVHISQISTERVNNVTDHLSEGQEVKVKVLEVDRQGRVRLSIKEAMESAAPAADAPTDA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR954246
EMBL· GenBank· DDBJ
CAI86079.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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