Q3IF41 · ACCD_PSET1
- ProteinAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- GeneaccD
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids291 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
Catalytic activity
- acetyl-CoA + N6-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N6-biotinyl-L-lysyl-[protein]
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | acetyl-CoA carboxylase complex | |
Molecular Function | acetyl-CoA carboxylase activity | |
Molecular Function | ATP binding | |
Molecular Function | carboxyl- or carbamoyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | malonyl-CoA biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta
- EC number
- Short namesACCase subunit beta ; Acetyl-CoA carboxylase carboxyltransferase subunit beta
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Alteromonadales > Pseudoalteromonadaceae > Pseudoalteromonas
Accessions
- Primary accessionQ3IF41
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000359032 | 1-291 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | |||
Sequence: MSWLEKILPKTTKASGRKEIPEGVWAKCTSCDSILYKAELEKALNVCPKCDHHMRISGRKRLEYFLDEGDRVELGTQHEPKDVLKFRDSKKYSDRITAAQKSSGEKDALVAMKGHLKGIPVAAVAFEFSFMGGSMASVVGARFVDAVDQCLEHNMPLICFSASGGARMQEALISLMQMAKTSAALAKMTEKGLPFISVMTDPTMGGVSASLAMLGDINVGEPKALIGFAGPRVIEQTVRETLPEGFQRSEFLLEHGAIDMIIDRREMRDTLARILAKFMNLPSTEQEHRVA |
Interaction
Subunit
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 24-291 | CoA carboxyltransferase N-terminal | ||||
Sequence: VWAKCTSCDSILYKAELEKALNVCPKCDHHMRISGRKRLEYFLDEGDRVELGTQHEPKDVLKFRDSKKYSDRITAAQKSSGEKDALVAMKGHLKGIPVAAVAFEFSFMGGSMASVVGARFVDAVDQCLEHNMPLICFSASGGARMQEALISLMQMAKTSAALAKMTEKGLPFISVMTDPTMGGVSASLAMLGDINVGEPKALIGFAGPRVIEQTVRETLPEGFQRSEFLLEHGAIDMIIDRREMRDTLARILAKFMNLPSTEQEHRVA | ||||||
Zinc finger | 28-50 | C4-type | ||||
Sequence: CTSCDSILYKAELEKALNVCPKC |
Sequence similarities
Belongs to the AccD/PCCB family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length291
- Mass (Da)32,039
- Last updated2005-11-08 v1
- Checksum22C69B0AE58F73F4
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CR954246 EMBL· GenBank· DDBJ | CAI87130.1 EMBL· GenBank· DDBJ | Genomic DNA |