Q39UD3 · Q39UD3_GEOMG

Function

Catalytic activity

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

Note: Binds 1 [4Fe-4S] cluster per subunit.

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.
Organic acid metabolism; propanoate degradation.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site190substrate
Binding site233-235substrate
Binding site403-405substrate
Binding site487substrate
Binding site703[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site762[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site765[4Fe-4S] cluster (UniProtKB | ChEBI)
Binding site784substrate
Binding site789substrate

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Function2-methylisocitrate dehydratase activity
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionaconitate hydratase activity
Molecular Functionmetal ion binding
Molecular FunctionRNA binding
Biological Processpropionate catabolic process, 2-methylcitrate cycle
Biological Processtricarboxylic acid cycle

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aconitate hydratase B
  • EC number
  • Alternative names
    • 2-methylisocitrate dehydratase

Gene names

    • Name
      acnB
    • Ordered locus names
      Gmet_1912

Organism names

Accessions

  • Primary accession
    Q39UD3

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-155Aconitase B HEAT-like
Domain167-371Aconitase B swivel
Domain461-689Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha
Domain690-810Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha

Sequence similarities

Belongs to the aconitase/IPM isomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    847
  • Mass (Da)
    91,141
  • Last updated
    2005-11-22 v1
  • Checksum
    22B62FC749FA30B6
MIEAYLAHEAERKAQGIPALPLNPEQTADLCNLLQNPPAGKEEFLLNLLKERVSPGVDPAAKVKAAFLAEIVKGTKKSPLVSKVDAIRILGTMIGGYNVGPLVEALKDAELAEEAACALSRMTLVYDGFDQVVELSKSNAAAKKVLESWANAEWFTNRPGVPETIKVKVFKVEGEINTDDFSPAGDAWSRPDIPLHALAMGKTRFPNRLKDIADWRAAGHQVAFVGDVVGTGSSRKSACNSVLWHMGQDIPAVPNKKTAGVIIGGVIAPIFFNTAQDSGALPLKADVTKMNDGDVITINTAKGEISNDKGEVISTFKISPNTLADEFRAGGRIPLIIGRAITEKARKALGLGDTDVFTKPVNPAPKAGQGYSLAQKMVGKACGVAGILPGTACEPKMTTVGSQDTTGPMTADELKELACLKFLSPMFMQSFCHTAAYPKPADVKMHKNLPGFIIERGGVPLKPGDGVIHSWLNRLLLPDTVGTGGDSHTRFPIGISFPAGSGLVAFAGAMGFMPLDMPESVLVRFKGKLNPGITLRDAVNAIPYWAIKQGKLTVPKKNKINIFNGRILEMEGLPDLTVEQAFELTDAAAERSAAAGCIQLSKESVATYLRSNVALMKKMIADGYQDAQTLQNRIDAVNEWLKNPQLLEADKNAVETGAYADVIEIDLAEITEPILACPNDPDDVKLLSDVAGTPIQDVFLGSCMTNIGHFRAAAEIWRGLKFNPSVRTWICPPTRMDQKQLKDEAYFSVYSAFGARIEIAGCSLCMGNQARVPDGVNMFSTSTRNFDDRIGDGAKVFLGSAELGAVTATLGKLPTVAEFMAAYKEKVEPKKDVVYKYLQFDEMPEYK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000148
EMBL· GenBank· DDBJ
ABB32141.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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