Q39839 · NDK1_SOYBN
- ProteinNucleoside diphosphate kinase 1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids149 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Catalytic activity
- a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 10 | ATP (UniProtKB | ChEBI) | |||
Binding site | 58 | ATP (UniProtKB | ChEBI) | |||
Binding site | 86 | ATP (UniProtKB | ChEBI) | |||
Binding site | 92 | ATP (UniProtKB | ChEBI) | |||
Binding site | 103 | ATP (UniProtKB | ChEBI) | |||
Binding site | 113 | ATP (UniProtKB | ChEBI) | |||
Active site | 116 | Pros-phosphohistidine intermediate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | nucleoside diphosphate kinase activity | |
Biological Process | CTP biosynthetic process | |
Biological Process | GTP biosynthetic process | |
Biological Process | UTP biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNucleoside diphosphate kinase 1
- EC number
- Alternative names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fabales > Fabaceae > Papilionoideae > 50 kb inversion clade > NPAAA clade > indigoferoid/millettioid clade > Phaseoleae > Glycine > Glycine subgen. Soja
Accessions
- Primary accessionQ39839
Proteomes
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length149
- Mass (Da)16,443
- Last updated1996-11-01 v1
- MD5 Checksum48B1802DD55FD8B667678144CF1B5BD2
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U50150 EMBL· GenBank· DDBJ | AAA93030.1 EMBL· GenBank· DDBJ | mRNA |