Q39232 · SUC1_ARATH

Function

function

Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system). This transport is both voltage- and energy-dependent. Can also transport other glucosides such as maltose, alpha-phenylglucoside and beta-phenylglucoside. May also transport biotin. Required for normal pollen germination and anthocyanin accumulation induced by sucrose.

Catalytic activity

Activity regulation

Inhibited by DEPC, protonophores (e.g. dinitrophenol and carbonyl cyanide m-chlorophenyl-hydrazone (CCCP)), and SH group inhibitors (e.g. N-ethylmaleimide (NEM) and p-chloromercuriphenyl sulphonic acid (PCMPS)).

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
450 μMsucrose5.530
Vmax pH TEMPERATURE[C] NOTES EVIDENCE
45 μmol/h/g(without glucose)
154 μmol/h/g(in the presence of 10 mM glucose)

pH Dependence

Optimum pH is 5-6.

Pathway

Glycan biosynthesis; sucrose metabolism.

GO annotations

AspectTerm
Cellular Componentmitochondrion
Cellular Componentplasma membrane
Cellular Componentplasmodesma
Cellular Componentvacuole
Molecular Functionsucrose:proton symporter activity
Biological Processpollen germination
Biological Processresponse to nematode
Biological Processsucrose metabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

    • 2.A.2.4.1the glycoside-pentoside-hexuronide (gph):cation symporter family

Names & Taxonomy

Protein names

  • Recommended name
    Sucrose transport protein SUC1
  • Short names
    AtSUC1
  • Alternative names
    • Sucrose permease 1
    • Sucrose-proton symporter 1

Gene names

    • Name
      SUC1
    • ORF names
      F17M19.3
    • Ordered locus names
      At1g71880

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q39232

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for topological domain, transmembrane.

Type
IDPosition(s)Description
Topological domain1-32Cytoplasmic
Transmembrane33-53Helical
Topological domain54-67Extracellular
Transmembrane68-88Helical
Topological domain89-101Cytoplasmic
Transmembrane102-122Helical
Topological domain123-139Extracellular
Transmembrane140-160Helical
Topological domain161-178Cytoplasmic
Transmembrane179-199Helical
Topological domain200-224Extracellular
Transmembrane225-245Helical
Topological domain246-282Cytoplasmic
Transmembrane283-303Helical
Topological domain304-334Extracellular
Transmembrane335-355Helical
Topological domain356-365Cytoplasmic
Transmembrane366-386Helical
Topological domain387-408Extracellular
Transmembrane409-429Helical
Topological domain430-441Cytoplasmic
Transmembrane442-462Helical
Topological domain463-474Extracellular
Transmembrane475-495Helical
Topological domain496-513Cytoplasmic

Keywords

Phenotypes & Variants

Disruption phenotype

Defective pollen with low rate of germination. Reduction of anthocyanin accumulation in response to exogenous sucrose or maltose.

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis65No sucrose transport activity, high instability.
Mutagenesis65Reduced sucrose transport activity.
Mutagenesis65Enhanced sucrose transport activity.
Mutagenesis65Reduced sensitivity to DEPC.
Mutagenesis65Enhanced sucrose transport activity, reduced sensitivity to DEPC.
Mutagenesis65Reduced sucrose transport activity, reduced sensitivity to DEPC.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 16 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_00001225221-513Sucrose transport protein SUC1
Modified residue20Phosphoserine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in flowers (at protein level). Highly expressed in pollen. Expressed in pollen tubes and root vascular cylinder, pericycle and endodermis.

Induction

By exogenous sucrose in roots. Induced by sucrose depletion.

Developmental stage

Transcripts accumulate in mature pollen before and during germination, but translation starts only when pollen germination initiates, and continues in pollen tubes. Expressed in cells surrounding the vascular bundle of the anther connective tissue, mostly at the dehiscence time. Also present in a ring of parenchymatic cells between the xylem vessels of the style (upper end of the transmitting tract toward which pollen tubes grow). Expressed in the epidermal cell layers of funiculi (at protein level).

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias1-11Basic and acidic residues
Region1-26Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    513
  • Mass (Da)
    54,858
  • Last updated
    1996-11-01 v1
  • MD5 Checksum
    C35046ECFCF4CE0C90E638A7B6E8E9FD
MGAYETEKPTKDAAALETQSPEDFDQPSPLRKIISVASIAAGVQFGWALQLSLLTPYVQLLGIPHKWSSLIWLCGPVSGMIVQPIVGFHSDRCRSKFGRRRPFIATGAALVAVAVFLIGYAADFGYKMGDKLEEKVKVRAIGIFALGFWILDVANNTLQGPCRAFLADLAAGDAKRTRVANAFFSFFMAVGNVLGYAAGSYTNLHKMFPFTMTKACDIYCANLKTCFFLSITLLLIVTVTSLWYVNDKQWSPPPRNADDDEKTSSVPLFGEIFGAFKVMKRPMWMLLIVTALNWIAWFPFLLFDTDWMGREVFGGDSDGNERSKKLYSLGVQSGAMGLMFNSIVLGFMSLGVEWIGRKLGGAKRLWGIVNFILAAGLAMTVLVTKFAEDHRKTAGDLAGPSASVKAGALSLFAVLGIPLAITFSTPFALASIFSSCSGAGQGLSLGVLNLAIVIPQMIVSLGGGPFDALFGGGNLPAFIVAAIAAAISGVLALTVLPSPPPDAPKATTMGGFH

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-11Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X75365
EMBL· GenBank· DDBJ
CAA53147.1
EMBL· GenBank· DDBJ
mRNA
AC021665
EMBL· GenBank· DDBJ
AAG52225.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE35247.1
EMBL· GenBank· DDBJ
Genomic DNA
AY049275
EMBL· GenBank· DDBJ
AAK83617.1
EMBL· GenBank· DDBJ
mRNA
BT020416
EMBL· GenBank· DDBJ
AAV97807.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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