Q39017 · DGK1_ARATH
- ProteinDiacylglycerol kinase 1
- GeneDGK1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids728 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Phosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress (By similarity).
Miscellaneous
Treatment with (E)-2-hexenal, (Z)-3-hexenal and allo-ocimene increases plant resistance against the necrotrophic fungal pathogen Botrytis cinerea.
Catalytic activity
- a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H+
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | ATP binding | |
Molecular Function | calcium ion binding | |
Molecular Function | kinase activity | |
Biological Process | defense response | |
Biological Process | phospholipase C-activating G protein-coupled receptor signaling pathway | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDiacylglycerol kinase 1
- EC number
- Short namesAtDGK1; DAG kinase 1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ39017
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 27-48 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, cross-link.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000218475 | 1-728 | Diacylglycerol kinase 1 | ||
Cross-link | 491 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) | |||
Cross-link | 500 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) | |||
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Expressed in roots, shoots, and leaves.
Induction
By volatile C6-aldehydes ((E)-2-hexenal, (Z)-3-hexenal, (Z)-3-hexenol), and allo-ocimene.
Gene expression databases
Interaction
Structure
Family & Domains
Features
Showing features for zinc finger, region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Zinc finger | 79-137 | Phorbol-ester/DAG-type 1 | |||
Zinc finger | 149-212 | Phorbol-ester/DAG-type 2 | |||
Region | 265-296 | Disordered | |||
Region | 308-336 | Disordered | |||
Compositional bias | 319-333 | Basic and acidic residues | |||
Domain | 357-496 | DAGKc | |||
Sequence similarities
Belongs to the eukaryotic diacylglycerol kinase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length728
- Mass (Da)79,984
- Last updated2002-03-27 v2
- Checksum9E3190721C083DE9
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8BCS4 | A0A1P8BCS4_ARATH | DGK1 | 687 |
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 319-333 | Basic and acidic residues | |||
Sequence conflict | 509 | in Ref. 1; BAA09856 | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
D63787 EMBL· GenBank· DDBJ | BAA09856.1 EMBL· GenBank· DDBJ | mRNA | ||
AL133421 EMBL· GenBank· DDBJ | CAB62604.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AB005249 EMBL· GenBank· DDBJ | BAB09956.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | AED91221.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002688 EMBL· GenBank· DDBJ | ANM69404.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BT004148 EMBL· GenBank· DDBJ | AAO42169.1 EMBL· GenBank· DDBJ | mRNA |