Q38ZE5 · FLUC1_LATSS

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site75Na+ (UniProtKB | ChEBI); structural
Binding site78Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC 1

Gene names

    • Name
      fluC1
    • Synonyms
      crcB1
    • Ordered locus names
      LCA_0135

Organism names

Accessions

  • Primary accession
    Q38ZE5

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-27Helical
Transmembrane32-52Helical
Transmembrane65-85Helical
Transmembrane96-116Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002528921-135Fluoride-specific ion channel FluC 1

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    135
  • Mass (Da)
    14,863
  • Last updated
    2005-11-22 v1
  • Checksum
    5807FFF33EABD6AD
MKIKESLAVGSFAFFGGILRYLIGLVLNQPTGFPYGTLCVNLIGAFCLPFLMRYIVARLHLSDQLALAIGTGFFGAFTTFSSFSVDAIRLVNQQQWSAFAWYVGISMVGGVLLSLLADYWAVKLTHNPEEQEVSQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR936503
EMBL· GenBank· DDBJ
CAI54432.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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