Q38ZE5 · FLUC1_LATSS
- ProteinFluoride-specific ion channel FluC 1
- GenefluC1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids135 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 75 | Na+ (UniProtKB | ChEBI); structural | |||
Binding site | 78 | Na+ (UniProtKB | ChEBI); structural | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC 1
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Latilactobacillus
Accessions
- Primary accessionQ38ZE5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 7-27 | Helical | |||
Transmembrane | 32-52 | Helical | |||
Transmembrane | 65-85 | Helical | |||
Transmembrane | 96-116 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000252892 | 1-135 | Fluoride-specific ion channel FluC 1 | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length135
- Mass (Da)14,863
- Last updated2005-11-22 v1
- Checksum5807FFF33EABD6AD
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CR936503 EMBL· GenBank· DDBJ | CAI54432.1 EMBL· GenBank· DDBJ | Genomic DNA |