Q38ZE4 · FLUC2_LATSS

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

1115102030405060708090100110
TypeIDPosition(s)Description
Binding site68Na+ (UniProtKB | ChEBI); structural
Binding site71Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC 2

Gene names

    • Name
      fluC2
    • Synonyms
      crcB2
    • Ordered locus names
      LCA_0136

Organism names

Accessions

  • Primary accession
    Q38ZE4

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane1-21Helical
Transmembrane31-51Helical
Transmembrane57-77Helical
Transmembrane91-111Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002528931-115Fluoride-specific ion channel FluC 2

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence

  • Sequence status
    Complete
  • Length
    115
  • Mass (Da)
    12,601
  • Last updated
    2005-11-22 v1
  • Checksum
    40A936961468F392
MTILLVGLGAALGAILRYQLTRIGNHIASEFPLMTFLINLTGSFCLGWLTGSQLSQPVTLFLGVGVLGGYTTFSTLNSELSQLWFRRRYHIFFGYWLLTYGLGLLVAAAGFYAGL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CR936503
EMBL· GenBank· DDBJ
CAI54433.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help