Q38ZE4 · FLUC2_LATSS
- ProteinFluoride-specific ion channel FluC 2
- GenefluC2
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids115 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 68 | Na+ (UniProtKB | ChEBI); structural | |||
Binding site | 71 | Na+ (UniProtKB | ChEBI); structural | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC 2
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Latilactobacillus
Accessions
- Primary accessionQ38ZE4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 1-21 | Helical | |||
Transmembrane | 31-51 | Helical | |||
Transmembrane | 57-77 | Helical | |||
Transmembrane | 91-111 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000252893 | 1-115 | Fluoride-specific ion channel FluC 2 | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length115
- Mass (Da)12,601
- Last updated2005-11-22 v1
- Checksum40A936961468F392
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CR936503 EMBL· GenBank· DDBJ | CAI54433.1 EMBL· GenBank· DDBJ | Genomic DNA |