Q38WN0 · GCH1_LATSS
- ProteinGTP cyclohydrolase 1
- GenefolE
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids189 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H+
Pathway
Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTP cyclohydrolase I activity | |
Molecular Function | zinc ion binding | |
Biological Process | one-carbon metabolic process | |
Biological Process | tetrahydrobiopterin biosynthetic process | |
Biological Process | tetrahydrofolate biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGTP cyclohydrolase 1
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Lactobacillales > Lactobacillaceae > Latilactobacillus
Accessions
- Primary accessionQ38WN0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_1000058674 | 1-189 | GTP cyclohydrolase 1 | |||
Sequence: MIEQANQQIEKDVRDILKQVGDDPERAGVLETPQRVAKMYGEVLAYQGETIFKDYKLFETEETDDDQMVMMQDIPFYSMCEHHMLPFFGQVSVAYLPANGQIIGLSKIPRLVDFVSKRLSVQENLTRDIGQILNQILKPYGVAVQVTARHMCVEMRGIKKANSQTHTTFYSGNFKTDRQLRSEFLQLLK |
Interaction
Subunit
Toroid-shaped homodecamer, composed of two pentamers of five dimers.
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length189
- Mass (Da)21,753
- Last updated2005-11-22 v1
- Checksum794BE49D4429F813
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CR936503 EMBL· GenBank· DDBJ | CAI55401.1 EMBL· GenBank· DDBJ | Genomic DNA |