Q38F42 · Q38F42_TRYB2

Function

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Note: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

Features

Showing features for active site, binding site.

1925100200300400500600700800900
TypeIDPosition(s)Description
Active site669Proton donor
Binding site669-673AMP (UniProtKB | ChEBI)
Binding site673Zn2+ (UniProtKB | ChEBI)
Binding site673Zn2+ 1 (UniProtKB | ChEBI)
Binding site709Zn2+ 1 (UniProtKB | ChEBI)
Binding site709Zn2+ (UniProtKB | ChEBI)
Binding site710AMP (UniProtKB | ChEBI)
Binding site710Mg2+ (UniProtKB | ChEBI)
Binding site710Zn2+ 1 (UniProtKB | ChEBI)
Binding site710Zn2+ 2 (UniProtKB | ChEBI)
Binding site710Zn2+ (UniProtKB | ChEBI)
Binding site823AMP (UniProtKB | ChEBI)
Binding site823Zn2+ (UniProtKB | ChEBI)
Binding site823Zn2+ 1 (UniProtKB | ChEBI)
Binding site875AMP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentaxoneme
Cellular Componentcytoplasm
Molecular Function3',5'-cyclic-AMP phosphodiesterase activity
Molecular Function3',5'-cyclic-GMP phosphodiesterase activity
Molecular Function3',5'-cyclic-nucleotide phosphodiesterase activity
Molecular Functionmetal ion binding
Biological ProcesscAMP-mediated signaling

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphodiesterase
  • EC number

Gene names

    • ORF names
      Tb09.160.3630

Organism names

Accessions

  • Primary accession
    Q38F42

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Proteomic databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain590-919PDEase

Sequence similarities

Belongs to the cyclic nucleotide phosphodiesterase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    925
  • Mass (Da)
    103,218
  • Last updated
    2005-11-22 v1
  • Checksum
    8DEF862F8C012C46
MTHNGGRHLLEAVTLCGSILTRYKRSNMKLDEAEVRALKELFEKYQDILVDGSPGLPTHASGPMIQPPVTNMVAPYDSPTDTIVKFVEGTINLQRPIVEVLHVMNEHLSLVLRAKNTHVFYVDPVNNLLYDPIHGVAAALDESSPIGKAIVSGERLNVAGTLYIPIISEGMPLGCVLSPCGRADYHASTMLESSLRVISTSLKNIIQAEKLNWNKEKAEAMLRMATQLARDNLEETVLASSIMNTVKSLTESARCSLFLVRGDVLEAHFEDGNVVTIPRGAGIAGYVAQTGETVNIVDAYADDRFNREVDKATGYRTKTILCMPVMYEGTIVAVAQLINKLDLTTESGLRLPRVFGRRDEELFQTFSMFAGASLRNCRINDRLLKEKKKSDVILDVVTVLSNTDIRDVDGIVRHALHGAKKLLNADRSTLFLVDKERNELCSRMADSVAGKEIRFPCGQGIAGTVAASGVGENIQDAYQDPRFNREVDKQLGYRTQAILCEPIILNGEILAVVQLVNKLDSSGEVTVFTEDDRDTFRVFSLFAGISINNSHLLEFAVKAGREVMELNEHRATLFNKNVPSRGVKRVTAITNREREAVLRIEFPNVDVTDIDFDLFQARESTDKPLDVAAAIAYRLLLGSGLPQKFGCSDEVLLNFILQCRKKYRNVPYHNFYHVVDVCQTIYTFLYRGNVYEKLTELECFVLLITALVHDLDHMGLNNSFYLKTESPLGILSSASGNKSVLEVHHCNLAVEILSDPESDVFGGLEGAERTLAFRSMIDCVLATDMARHSEFLEKYLELMKTSYNVDDSDHRQMTMDVLMKAGDISNVTKPFDISRQWAMAVTEEFYRQGDMEKERGVEVLPMFDRSKNMELAKGQIGFIDFVAAPFFQKIVDACLQGMQWTVDRTKSNRAQWERVLEARSTGASS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CM000207
EMBL· GenBank· DDBJ
EAN76578.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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