Q38838 · AGL14_ARATH

Function

function

Transcriptional activator that regulates root development by controlling meristem size and patterning of the root apical meristem. Regulates auxin transport and gradients in the root meristematic cells via direct regulation of the auxin efflux carrier PIN1 and PIN4 gene expression. Binds specifically to the CArG-box DNA sequences in the promoter regions of PIN1 and PIN4 genes (PubMed:24121311).
Involved in the regulation of shoot apical meristem (SAM) cell identities and transitions. Promotes flowering transition and participates in flower meristem maintenance and determinacy. Positively regulates TFL1 and WUS expression. Binds directly to the TFL1 regulatory sequences (PubMed:25636918).

Miscellaneous

XAANTAL is the Mayan word for 'go slower' in recognition of the retarded root growth phenotypes of xaantal mutants.
Plants over-expressing AGL14/XAL2 show early flowering phenotype and flowers have vegetative traits.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity
Molecular Functionprotein dimerization activity
Molecular FunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding
Molecular Functiontranscription cis-regulatory region binding
Biological Processflower development
Biological Processmaintenance of floral meristem identity
Biological Processpositive regulation of transcription by RNA polymerase II
Biological Processregulation of auxin polar transport
Biological Processregulation of root meristem growth
Biological Processvegetative to reproductive phase transition of meristem

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Agamous-like MADS-box protein AGL14
  • Alternative names
    • Protein XAANTAL 2

Gene names

    • Name
      AGL14
    • Synonyms
      XAL2
    • ORF names
      T26M18.90
    • Ordered locus names
      At4g11880

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Columbia
    • cv. Landsberg erecta
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q38838
  • Secondary accessions
    • Q0WKU9
    • Q9T056

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

Retarded root growth, and altered root meristem size and stem-cell patterning (PubMed:24121311).
Late flowering phenotype (PubMed:25636918).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 19 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001994731-221Agamous-like MADS-box protein AGL14

Proteomic databases

Expression

Tissue specificity

Preferentially expressed in roots (PubMed:7549482).
Expressed in lateral root cap, root epidermis, root endodermis, columella of the root meristematic region, the vascular cylinder in differentiated zones of the primary root and in emerged lateral root primordia (PubMed:24121311).
Expressed in pollen (PubMed:12949148).

Induction

By auxin.

Developmental stage

During floral transition, expressed very early at the flanks of the inflorescence meristem in the anlagens upon the transition to flowering Subsequently, expression levels increase in the first and second stages of the floral meristem and at stage 3, expression is restricted to the L1 and L2 layers. Later on, expressed in the gynoecium and stamen primordia at stage 6.

Gene expression databases

Interaction

Subunit

Interacts with AGL16.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntAct
BINARY Q38838AGL24 O827946EBI-622067, EBI-592083
BINARY Q38838SVP Q9FVC14EBI-622067, EBI-592058

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-57MADS-box
Domain87-177K-box

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    221
  • Mass (Da)
    25,492
  • Last updated
    2001-01-11 v2
  • Checksum
    E876DAEA049B125E
MVRGKTEMKRIENATSRQVTFSKRRNGLLKKAFELSVLCDAEVALIIFSPRGKLYEFSSSSSIPKTVERYQKRIQDLGSNHKRNDNSQQSKDETYGLARKIEHLEISTRKMMGEGLDASSIEELQQLENQLDRSLMKIRAKKYQLLREETEKLKEKERNLIAENKMLMEKCEMQGRGIIGRISSSSSTSELDIDDNEMEVVTDLFIGPPETRHFKKFPPSN

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8B7Y6A0A1P8B7Y6_ARATHAGL14179

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict103in Ref. 4; AAC49082
Sequence conflict187-188in Ref. 4; AAC49082

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL078606
EMBL· GenBank· DDBJ
CAB44326.1
EMBL· GenBank· DDBJ
Genomic DNA
AL161532
EMBL· GenBank· DDBJ
CAB78231.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
AEE83062.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002687
EMBL· GenBank· DDBJ
ANM67706.1
EMBL· GenBank· DDBJ
Genomic DNA
AK230464
EMBL· GenBank· DDBJ
BAF02258.1
EMBL· GenBank· DDBJ
mRNA
U20184
EMBL· GenBank· DDBJ
AAC49082.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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