Q38825 · IAA7_ARATH

Function

function

Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity
Molecular Functiontranscription cis-regulatory region binding
Biological Processauxin-activated signaling pathway
Biological Processgravitropism
Biological Processresponse to auxin
Biological Processresponse to jasmonic acid
Biological Processresponse to water deprivation
Biological Processresponse to wounding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Auxin-responsive protein IAA7
  • Alternative names
    • Auxin resistant 2
    • Indoleacetic acid-induced protein 7

Gene names

    • Name
      IAA7
    • Synonyms
      AXR2
    • ORF names
      MXC7.8
    • Ordered locus names
      At3g23050

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q38825
  • Secondary accessions
    • Q8LAK1

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis87In axr2-1; gain of function. Affects auxin-related developmental processes. Affects photomorphogenesis.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 18 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001128381-243Auxin-responsive protein IAA7

Proteomic databases

PTM databases

Expression

Tissue specificity

Highly expressed in stems and flowers.

Induction

By auxin.

Gene expression databases

Family & Domains

Features

Showing features for motif, domain.

TypeIDPosition(s)Description
Motif13-17EAR-like (transcriptional repression)
Domain124-224PB1

Domain

The N-terminal half of the protein contains two conserved domains I and II. Domain I includes a slightly degenerated ERF-associated amphiphilic repression (EAR) motif which seems to be involved in the activity of transcriptional repression. Domain II is required for the correct degradation of the protein through the SCF-mediated ubiquitin-proteasome pathway. Interactions between Aux/IAA proteins and auxin response factors (ARFs) occur through their C-terminal dimerization domains III and IV.

Sequence similarities

Belongs to the Aux/IAA family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete

This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.

Q38825-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    243
  • Mass (Da)
    26,381
  • Last updated
    1996-11-01 v1
  • Checksum
    830E9B9EA2C2B5D0
MIGQLMNLKATELCLGLPGGAEAVESPAKSAVGSKRGFSETVDLMLNLQSNKEGSVDLKNVSAVPKEKTTLKDPSKPPAKAQVVGWPPVRNYRKNMMTQQKTSSGAEEASSEKAGNFGGGAAGAGLVKVSMDGAPYLRKVDLKMYKSYQDLSDALAKMFSSFTMGNYGAQGMIDFMNESKLMNLLNSSEYVPSYEDKDGDWMLVGDVPWEMFVESCKRLRIMKGSEAVGLAPRAMEKYCKNRS

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
F4J2U7F4J2U7_ARATHIAA7210
A0A1I9LPC8A0A1I9LPC8_ARATHIAA7167

Sequence caution

The sequence AAM65301.1 differs from that shown. Reason: Erroneous initiation

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict228in Ref. 5; AAM65301

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U18409
EMBL· GenBank· DDBJ
AAC49048.1
EMBL· GenBank· DDBJ
mRNA
AB026655
EMBL· GenBank· DDBJ
BAB02096.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002686
EMBL· GenBank· DDBJ
AEE76710.1
EMBL· GenBank· DDBJ
Genomic DNA
AF332395
EMBL· GenBank· DDBJ
AAG48759.1
EMBL· GenBank· DDBJ
mRNA
AY054651
EMBL· GenBank· DDBJ
AAK96842.1
EMBL· GenBank· DDBJ
mRNA
AY072461
EMBL· GenBank· DDBJ
AAL66876.1
EMBL· GenBank· DDBJ
mRNA
AY087765
EMBL· GenBank· DDBJ
AAM65301.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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