Q37395 · CYB_ALLMA

  • Protein
    Cytochrome b
  • Gene
    cob
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.

Miscellaneous

Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.

Caution

The protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 2 heme b groups non-covalently.

Features

Showing features for binding site.

138250100150200250300350
TypeIDPosition(s)Description
Binding site82Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site96Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site183Fe (UniProtKB | ChEBI) of heme b b562 (UniProtKB | ChEBI); axial binding residue
Binding site197Fe (UniProtKB | ChEBI) of heme b b566 (UniProtKB | ChEBI); axial binding residue
Binding site202a ubiquinone (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial respiratory chain complex III
Molecular Functionmetal ion binding
Molecular Functionubiquinol-cytochrome-c reductase activity
Biological Processmitochondrial electron transport, ubiquinol to cytochrome c

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cytochrome b
  • Alternative names
    • Complex III subunit 3
    • Complex III subunit III
    • Cytochrome b-c1 complex subunit 3
    • Ubiquinol-cytochrome-c reductase complex cytochrome b subunit

Gene names

    • Name
      cob
    • Synonyms
      cytB

Encoded on

  • Mitochondrion

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Fungi > Fungi incertae sedis > Blastocladiomycota > Blastocladiomycetes > Blastocladiales > Blastocladiaceae > Allomyces

Accessions

  • Primary accession
    Q37395

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane32-52Helical
Transmembrane76-98Helical
Transmembrane113-133Helical
Transmembrane179-199Helical
Transmembrane225-245Helical
Transmembrane289-309Helical
Transmembrane321-341Helical
Transmembrane348-368Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000617331-382Cytochrome b

Interaction

Subunit

Fungal cytochrome b-c1 complex contains 10 subunits; 3 respiratory subunits, 2 core proteins and 5 low-molecular weight proteins. Cytochrome b-c1 complex is a homodimer.

Structure

Family & Domains

Sequence similarities

Belongs to the cytochrome b family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    382
  • Mass (Da)
    43,468
  • Last updated
    1996-11-01 v1
  • Checksum
    A892A1A46A6915FA
MRFLKSHPVLSLANSFLIDSPLPSNITYLWNFGSLLGLCLVIQIVTGVTLAMHYAPSTSLAFVSVEHIMRDVFYGWLIRYAHANGASFFFICVYIHMARGLYFNSYTKPRVLLWSVGVVIYILMMATAFLGYVLPWGQMSFWGATVITNLLSAIPYIGTALVEFVWGGFSVDNATLNRFFSLHYLLPFILAALVVVHLIALHEHGSNNPLGISSKVDRLPFHPYFTYKDLVGFFVFFLIFFGFVFYQPNLMGHPDNYIPANPLVTPVSIVPEWYFLPFYAILRAIPSKLGGVIGMFGALLILLALPWLETSKVRGAGFRPVMKFFFWLFVVNFFLLMYCGGQHAEEPFITLSRICTAYYFMYFLVIIPVIGHLENLLHRCRD

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U41288
EMBL· GenBank· DDBJ
AAC49221.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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