Q33DX5 · RMTC_PROMI

  • Protein
    16S rRNA (guanine(1405)-N(7))-methyltransferase
  • Gene
    rmtC
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

function

Specifically methylates the N7 position of guanine 1405 in 16S rRNA. Confers resistance to various aminoglycosides, including gentamicin and kanamycin.

Catalytic activity

Features

Showing features for binding site.

128120406080100120140160180200220240260280
TypeIDPosition(s)Description
Binding site60S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site105-107S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site111S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site136S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site160S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site186-187S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site203S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site212S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular FunctionrRNA methyltransferase activity
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    16S rRNA (guanine(1405)-N(7))-methyltransferase
  • EC number
  • Alternative names
    • 16S rRNA m7G1405 methyltransferase

Gene names

    • Name
      rmtC

Encoded on

  • Plasmid pARS68

Organism names

  • Taxonomic identifier
  • Strains
    • ARS68
    • JIE273
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Proteus

Accessions

  • Primary accession
    Q33DX5

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004168191-28116S rRNA (guanine1405-N7)-methyltransferase

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    281
  • Mass (Da)
    32,106
  • Last updated
    2005-12-06 v1
  • Checksum
    BA1342B4A198A7AE
MKTNDNYIEEVTAKVLTSGKYSTLYPPTVRRVTERLFDRYPPKQLEKEVRKKLHQAYGAYIGGIDGKRLEKKIEKIIHEIPNPTTDEATRTEWEKEICLKILNLHTSTNERTVAYDELYQKIFEVTGVPTSITDAGCALNPFSFPFFTEAGMLGQYIGFDLDKGMIEAIEHSLRTLNAPEGIVVKQGDILSDPSGESDLLLMFKLYTLLDRQEEASGLKILQEWKYKNAVISFPIKTISGRDVGMEENYTVKFENDLVGSDLRIMQKLKLGNEMYFIVSRL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB194779
EMBL· GenBank· DDBJ
BAE48305.1
EMBL· GenBank· DDBJ
Genomic DNA
EU144360
EMBL· GenBank· DDBJ
ABX39521.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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