Q338Z4 · Q338Z4_ORYSJ

Function

function

Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
FMN (UniProtKB | Rhea| CHEBI:58210 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: Binds 1 potassium ion per subunit.

Pathway

Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.
Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site150-154(6S)-NADPHX (UniProtKB | ChEBI)
Binding site151K+ (UniProtKB | ChEBI)
Binding site215K+ (UniProtKB | ChEBI)
Binding site219-225(6S)-NADPHX (UniProtKB | ChEBI)
Binding site256(6S)-NADPHX (UniProtKB | ChEBI)
Binding site259K+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentchloroplast
Cellular Componentcytosol
Cellular Componentmitochondrion
Molecular FunctionFMN binding
Molecular Functionmetal ion binding
Molecular FunctionNADHX epimerase activity
Molecular FunctionNADPHX epimerase activity
Molecular Functionpyridoxamine phosphate oxidase activity
Biological ProcessNADH metabolic process
Biological ProcessNADP metabolic process
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD(P)H-hydrate epimerase
  • EC number
  • Alternative names
    • NAD(P)HX epimerase

Gene names

    • ORF names
      OSNPB_100377800
    • Ordered locus names
      LOC_Os10g23120
      , Os10g0377800

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    Q338Z4

Proteomes

Genome annotation databases

Subcellular Location

PTM/Processing

Features

Showing features for modified residue (large scale data).

TypeIDPosition(s)SourceDescription
Modified residue (large scale data)462PTMeXchangePhosphoserine
Modified residue (large scale data)547PTMeXchangePhosphoserine

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region31-58Disordered
Domain100-315YjeF N-terminal

Sequence similarities

Belongs to the NnrE/AIBP family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    548
  • Mass (Da)
    60,478
  • Last updated
    2005-12-06 v1
  • Checksum
    30147AB2871CBEB9
MLTVAASALRNNKKSTAAACFSLAMPFLLSSPTPPPPPHSSSLPRSPSPRPRLPLPPPRRAALVTAAQDPRWRRAMASLAVSASASASGEEVTHLAQREAAEIDEQLMGPLGFSVDQLMELAGLSVAAAVAEVYKLGEHTRVLVICGPGNNGGDGLVAARHLHHFGYKPSVCYPKRTPKPLYSGLCTQLESLTIPFVPVEDLPANLSEEFDIIIDAMFGFSFHGTPRPPFDDLINRLVSLSAIDNSAKRPAIVSVDIPSGWHVEEGDINGGGFKPDMLVSLTAPKLCAKKFTGPHHFLGGRFVPPPIVSKYKLHLPPYPGTSMCVRIGKAPSVDISSLRENYISPELLENQVMPDPFDQFVRWFDEAVTAGLREPNAMALTTADKEGKPSSRMVLLKGVDKQGFVWYTNYGSQKAHDLSENPNAALLFYWNEMNRQVRVEGSVQKVPEEESEKYFHSRPRGSQLGAIVSKQSTIIPGREVLQQAYKELEQKYSDGSVIPKPDYWGGYRLTPKLFEFWQGQQSRLHDRLQYSLREVDRSTVWHIERLSP

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0P0XTG9A0A0P0XTG9_ORYSJOs10g0377800523
A0A0P0XTK4A0A0P0XTK4_ORYSJOs10g0377800325

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DP000086
EMBL· GenBank· DDBJ
ABB47388.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014966
EMBL· GenBank· DDBJ
BAT10606.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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