Q32NC0 · CR021_HUMAN
- ProteinUPF0711 protein C18orf21
- GeneC18orf21
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids220 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUPF0711 protein C18orf21
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Homo
Accessions
- Primary accessionQ32NC0
- Secondary accessions
Proteomes
Organism-specific databases
Disease & Variants
Features
Showing features for natural variant.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Natural variant | VAR_030903 | 132 | in dbSNP:rs2276314 | |||
Sequence: T → A |
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 253 variants from UniProt as well as other sources including ClinVar and dbSNP.
Organism-specific databases
Miscellaneous
Genetic variation databases
PTM/Processing
Features
Showing features for chain, modified residue, modified residue (large scale data).
Type | ID | Position(s) | Source | Description | |||
---|---|---|---|---|---|---|---|
Chain | PRO_0000279448 | 1-220 | UniProt | UPF0711 protein C18orf21 | |||
Sequence: MRQKHYLEAAARGLHDSCPGQARYLLWAYTSSHDDKSTFEETCPYCFQLLVLDNSRVRLKPKARLTPKIQKLLNREARNYTLSFKEAKMVKKFKDSKSVLLITCKTCNRTVKHHGKSRSFVSTLKSNPATPTSKLSLKTPERRTANPNHDMSGSKGKSPASVFRTPTSGQSVSTCSSKNTSKTKKHFSQLKMLLSQNESQKIPKVDFRNFLSSLKGGLLK | |||||||
Modified residue | 126 | UniProt | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 126 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue | 130 | UniProt | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 130 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 132 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue | 139 | UniProt | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 152 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 158 | PRIDE | Phosphoserine | ||||
Sequence: S | |||||||
Modified residue (large scale data) | 165 | PRIDE | Phosphothreonine | ||||
Sequence: T | |||||||
Modified residue (large scale data) | 195 | PRIDE | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 117-181 | Disordered | ||||
Sequence: SRSFVSTLKSNPATPTSKLSLKTPERRTANPNHDMSGSKGKSPASVFRTPTSGQSVSTCSSKNTS | ||||||
Compositional bias | 120-181 | Polar residues | ||||
Sequence: FVSTLKSNPATPTSKLSLKTPERRTANPNHDMSGSKGKSPASVFRTPTSGQSVSTCSSKNTS |
Sequence similarities
Belongs to the UPF0711 family.
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
This entry describes 2 isoforms produced by Alternative splicing.
Q32NC0-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length220
- Mass (Da)24,827
- Last updated2005-12-06 v1
- Checksum3BB72C83F47F14EF
Q32NC0-2
- Name2
- Differences from canonical
- 1-88: Missing
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
L7N2F3 | L7N2F3_HUMAN | C18orf21 | 110 | ||
K7EM84 | K7EM84_HUMAN | C18orf21 | 88 | ||
A0A087X0E7 | A0A087X0E7_HUMAN | C18orf21 | 130 |
Sequence caution
Features
Showing features for alternative sequence, compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Alternative sequence | VSP_055184 | 1-88 | in isoform 2 | |||
Sequence: Missing | ||||||
Compositional bias | 120-181 | Polar residues | ||||
Sequence: FVSTLKSNPATPTSKLSLKTPERRTANPNHDMSGSKGKSPASVFRTPTSGQSVSTCSSKNTS | ||||||
Sequence conflict | 212 | in Ref. 2; AAK07541 | ||||
Sequence: S → F |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY631401 EMBL· GenBank· DDBJ | AAT51696.1 EMBL· GenBank· DDBJ | mRNA | ||
BC025950 EMBL· GenBank· DDBJ | - | mRNA | No translation available. | |
BC108730 EMBL· GenBank· DDBJ | AAI08731.1 EMBL· GenBank· DDBJ | mRNA | ||
BC119765 EMBL· GenBank· DDBJ | AAI19766.1 EMBL· GenBank· DDBJ | mRNA | ||
BC119766 EMBL· GenBank· DDBJ | AAI19767.1 EMBL· GenBank· DDBJ | mRNA | ||
AF277182 EMBL· GenBank· DDBJ | AAK07541.1 EMBL· GenBank· DDBJ | mRNA | Different initiation | |
AF277189 EMBL· GenBank· DDBJ | AAK07547.1 EMBL· GenBank· DDBJ | mRNA | Sequence problems. |