Q32MU4 · Q32MU4_MOUSE

  • Protein
    Transporter
  • Gene
    Slc6a4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site.

163050100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site94Na+ 1 (UniProtKB | ChEBI)
Binding site96Na+ 1 (UniProtKB | ChEBI)
Binding site97Na+ 1 (UniProtKB | ChEBI)
Binding site101Na+ 1 (UniProtKB | ChEBI)
Binding site336Na+ 1 (UniProtKB | ChEBI)
Binding site368Na+ 1 (UniProtKB | ChEBI)
Binding site434Na+ 1 (UniProtKB | ChEBI)
Binding site437Na+ 1 (UniProtKB | ChEBI)
Binding site438Na+ 1 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendosome membrane
Cellular Componentfocal adhesion
Cellular Componentneuron projection
Cellular Componentplasma membrane
Cellular Componentpresynapse
Molecular Functionantiporter activity
Molecular Functionmetal ion binding
Molecular Functionserotonin:sodium:chloride symporter activity
Biological Processregulation of thalamus size

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transporter

Gene names

    • Name
      Slc6a4

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q32MU4

Organism-specific databases

Subcellular Location

Cell junction, focal adhesion
Cell membrane
; Multi-pass membrane protein
Endomembrane system
; Multi-pass membrane protein
Endosome membrane
; Multi-pass membrane protein
Membrane
; Multi-pass membrane protein
Synapse

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane88-106Helical
Transmembrane118-139Helical
Transmembrane160-188Helical
Transmembrane251-268Helical
Transmembrane280-306Helical
Transmembrane326-350Helical
Transmembrane362-387Helical
Transmembrane422-443Helical
Transmembrane464-488Helical
Transmembrane500-523Helical
Transmembrane535-558Helical
Transmembrane570-595Helical

Keywords

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond200↔209

Keywords

Family & Domains

Features

Showing features for region, domain, compositional bias.

TypeIDPosition(s)Description
Region1-63Disordered
Domain24-64Sodium:neurotransmitter symporter serotonin N-terminal
Compositional bias45-63Polar residues

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    630
  • Mass (Da)
    70,148
  • Last updated
    2005-12-06 v1
  • Checksum
    F37EF1EC1764FB30
METTPLNSQKVLSECKDKEDCQENGVLQKGVPTPADKAEPGQISNGYSAVPSTSAGDEAPHSTPAATTTLVAEIHQGERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIIAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFAQDNITWTLHSTSPAEEFYLRHVLQIHQSKGLQDLGTISWQLALCIMLIFTIIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGATLPGAWRGVVFYLKPNWQKLLETGVWVDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHIWAKRREWFVLIVVITCILGSLLTLTSGGAYVVTLLEEYATGPAVLTVALIEAVVVSWFYGITQFCSDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPHWSIILGYCIGTSSVICIPIYIIYRLISTPGTLKERIIKSITPETPTEIPCGDIRMNAV

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias45-63Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC108978
EMBL· GenBank· DDBJ
AAI08979.1
EMBL· GenBank· DDBJ
mRNA
BC108979
EMBL· GenBank· DDBJ
AAI08980.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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