Q31IC8 · RLMKL_HYDCU
- ProteinRibosomal RNA large subunit methyltransferase K/L
- GenerlmL
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids734 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
Catalytic activity
- guanosine2445 in 23S rRNA + S-adenosyl-L-methionine = H+ + N2-methylguanosine2445 in 23S rRNA + S-adenosyl-L-homocysteine
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | 23S rRNA (guanine(2445)-N(2))-methyltransferase activity | |
Molecular Function | RNA binding | |
Molecular Function | rRNA (guanine-N7-)-methyltransferase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameRibosomal RNA large subunit methyltransferase K/L
Including 2 domains:
- Recommended name23S rRNA m2G2445 methyltransferase
- EC number
- Alternative names
- Recommended name23S rRNA m7G2069 methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Thiotrichales > Piscirickettsiaceae > Hydrogenovibrio
Accessions
- Primary accessionQ31IC8
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000366845 | 1-734 | Ribosomal RNA large subunit methyltransferase K/L | |||
Sequence: MCRFFATAPKGLNELLREELTTFGAENIKTQPTGATFDGDLEVGYRSCLWSRLANRIYLVLLETELPNQEALSSVVQSIDWSKHIDKEGTFAVSFSGQGLGITHSHYGALKIKDGIVDYFREHYQVRPSIDTEVPDIRVHGHLNRNQLTLSLDLSGYSLHQRGYREGIQVEAPLKENVAAAILMRANWPEIAQQGGAFYDPMCGSGTFLVEAALMASDTAPGVAKSGEMLLNYWLGHDESLWQKLVEEAEQREQVGLKHLPNIYGSDISHKSLDVARNSIQAAGYDDVIEIKQMAVEQGRKWGDWSPGLIVCNPPYGERLGEEETVKQIYLKLGEYLKAEFIHWKAAILTCHTELGMFLGIKAKRSHDFFNGAMSCRLFRFEIEEEWFRQPALQPKQDLAEQVLQLQPDLADTDNAKMVSNRIRKNMKGLKSWVKQNDISAYRVYDADIPEYALAIDLYDTLESGLWVVVAEYAPPKTVNPTKAKRRLYEAMSVLPSVFNVSPERIVFKVRSQQKGQDQYERLDEQKAFFTIVENQTRLRVNFTDYLDTGIFLDHRQVRQEVAKLAAGKRLLNLFCYTATATAEAVKAGCKSSLSLDMSKTYLYWAKHNFMCNDINEKQHVLQQENVLEWLETATQNPKDLFDVIFLDPPSFSTSKRMDGTLDIQRDHVDLIQKTLKLLSKDGKLIFSTNLRKFKLDKASFEPDYQIENITQRTMPKDYARNMKIHQAWLFSRQ |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 43-154 | THUMP | ||||
Sequence: VGYRSCLWSRLANRIYLVLLETELPNQEALSSVVQSIDWSKHIDKEGTFAVSFSGQGLGITHSHYGALKIKDGIVDYFREHYQVRPSIDTEVPDIRVHGHLNRNQLTLSLDL |
Sequence similarities
Belongs to the methyltransferase superfamily. RlmKL family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length734
- Mass (Da)83,831
- Last updated2005-12-06 v1
- Checksum53B49B7E02CB326B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000109 EMBL· GenBank· DDBJ | ABB41095.1 EMBL· GenBank· DDBJ | Genomic DNA |