Q31HD6 · CSOCA_HYDCU

Function

function

Reversible hydration of carbon dioxide. This bacteria encodes at least 3 CA enzymes (PubMed:20400567).
Essential for chemolithotrophic carbon dioxide fixation, supplies CO2 to RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) in the carboxysome (Probable).

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 Zn2+ per monomer.

Activity regulation

Inhibited by ethoxyzolamide and dithiothreitol (in crude extracts upon expression in E.coli).

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site184Zn2+ (UniProtKB | ChEBI); catalytic
Active site186Proton acceptor
Binding site252Zn2+ (UniProtKB | ChEBI); catalytic
Binding site263Zn2+ (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentcarboxysome
Molecular Functioncarbonate dehydratase activity
Molecular Functionmetal ion binding
Biological Processcarbon fixation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Carboxysome shell carbonic anhydrase
  • EC number
  • Short names
    CsoSCA
  • Alternative names
    • Carbonic anhydrase
      (CA
      )
    • Carboxysome shell protein CsoS3

Gene names

    • Name
      csoS3
    • Ordered locus names
      Tcr_0841

Organism names

Accessions

  • Primary accession
    Q31HD6

Subcellular Location

Carboxysome
Note: This bacterium makes alpha-type carboxysomes.

Keywords

Phenotypes & Variants

Disruption phenotype

Cells do not grow in low DIC levels. Cells lose carboxysomes when grown under low DIC conditions. Accumulates intracellular DIC normally, poor CO2 fixation.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004520631-528Carboxysome shell carbonic anhydrase

Expression

Induction

Induced by growth in low levels of dissolved inorganic carbon (DIC) (at protein level).

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region17-47Disordered
Compositional bias27-47Polar residues

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    528
  • Mass (Da)
    59,254
  • Last updated
    2005-12-06 v1
  • Checksum
    BFB6FFBD712B8484
MNRLKKSHRQKSLFWRPIAPNPRWQKENPTAHGSTDTGGFGYNGGNEEVKTSSTMMNGIHALVNERQNEWLRGYEVDIKSRFDNIESVLKDILAQQSQLNFVSWANQQLFAKLGVSLTEQDWQSGVQLQSQKGFQFLYGKTLFAQFMRMSEDFFVNDPLSGQRKQEAERMFKEAGFHAVGIAPCADGRLAHILSYVLRLPYALARRKAHAGVMFDVSESVRNWVFIEHTRFRDGQPNLADEPTRYLKIAVYHFSKADPTHQGCAAHGSDDHKAAQAALQKLKDFKQAIENRFGCGSTVQTLLLGLNTDDDSMKVHIPNASGEVCLDRYVETEQLYQATMNLPDSEAKQALENAIVTCNQALGSTAPQPELVKLLSWLIGNNFSQIAYVNQYENGCYSDIGHAERFIGIGNGFEEVQLRNLSYYSFLDTVEEGVNDVDVGIKIFKGLNVKKGLPIPIIIRCDYDGRVPGSKDRAEAKALRIEKALHNRYQELSAPGLLQTLPTLRDFTSCKPAERLPGLADLSAKQRTA

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias27-47Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000109
EMBL· GenBank· DDBJ
ABB41437.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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