Q31G52 · LPXD_HYDCU

Function

function

Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

Catalytic activity

Pathway

Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.

Features

Showing features for active site.

134750100150200250300
TypeIDPosition(s)Description
Active site240Proton acceptor

GO annotations

AspectTerm
Molecular FunctionN-acyltransferase activity
Biological Processlipid A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-3-O-acylglucosamine N-acyltransferase
  • EC number

Gene names

    • Name
      lpxD
    • Ordered locus names
      Tcr_1276

Organism names

Accessions

  • Primary accession
    Q31G52

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002644511-347UDP-3-O-acylglucosamine N-acyltransferase

Interaction

Subunit

Homotrimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxD subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    347
  • Mass (Da)
    37,256
  • Last updated
    2005-12-06 v1
  • MD5 Checksum
    BFBDA748FFFC6185F17FD6EFAB1337B2
MKLKNIVNYLKEVGIDVELKGDDSINVDQVSGLVEAQQNHISFLSDSKRIHELETTSAGVVLIHPKFESLTTTTCLLVENPYFAFAKVSQLLNPENFPAGIHASAVVDDSAKIAESAWIGENVVIGKRVTIGDNCYIGPGSVVLDDSVIGQKTRLVANVTVMHNCIIGEEGYLDPGCVIGGQGFGFANEQGEWHKIPQIGRVVIGDRVFVGVNANIHRGAINDTVIESNCIIDSLVHIAHNVSIGYGSAIASQVGFAGSTAVGKYCVFAGQAGINGHISIADKSYFAAKSGVTHTIKESGSYSGFPAIPTPEWQKNMVRSKGLNKMAQKIKHLEKELQELKSKLEND

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000109
EMBL· GenBank· DDBJ
ABB41871.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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