Q31DP9 · AROB_HYDCU

Function

function

Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Co2+ (UniProtKB | Rhea| CHEBI:48828 )

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 divalent metal cation per subunit. Can use either Co2+ or Zn2+.
NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site69-74NAD+ (UniProtKB | ChEBI)
Binding site103-107NAD+ (UniProtKB | ChEBI)
Binding site127-128NAD+ (UniProtKB | ChEBI)
Binding site140NAD+ (UniProtKB | ChEBI)
Binding site149NAD+ (UniProtKB | ChEBI)
Binding site167-170NAD+ (UniProtKB | ChEBI)
Binding site182Zn2+ (UniProtKB | ChEBI)
Binding site245Zn2+ (UniProtKB | ChEBI)
Binding site262Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Function3-dehydroquinate synthase activity
Molecular Functionmetal ion binding
Molecular Functionnucleotide binding
Biological Processamino acid biosynthetic process
Biological Processaromatic amino acid family biosynthetic process
Biological Processchorismate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-dehydroquinate synthase
  • EC number
  • Short names
    DHQS

Gene names

    • Name
      aroB
    • Ordered locus names
      Tcr_2136

Organism names

Accessions

  • Primary accession
    Q31DP9

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002311401-3583-dehydroquinate synthase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    358
  • Mass (Da)
    39,132
  • Last updated
    2005-12-06 v1
  • Checksum
    2E1E4A2823678C0D
MKTLTVELGERSYPIFIGQGLLGQAELFKPYVTGTQVLIVSNTTVAPLYLEKAKQAFSGYDVKTVILPDGEQYKNLDVLNQIFDVAIENRFDRKCTFVALGGGVIGDMTGFAAASYQRGVNFIQIPTTLLSQVDSSVGGKTGVNHPKGKNMIGAFHQPECVVIDTDTLNTLEDRELSAGLAEVIKYGLIVDYPFFEWLEQNLPGLLARDPVVLAEAIERSCQNKATIVAKDEKEAGLRALFNLGHTFGHAIEAGMGYGNWLHGEGVSAGMMQAVYLSKLMGDLTQTDQKRIAAILQSAHLPVMPPKEMSVQQFLDLMAGDKKVQAGQIRLVLLKAIGQAYVTGDYPAELLERTLIEYR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000109
EMBL· GenBank· DDBJ
ABB42724.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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