Q312S1 · DCTMQ_OLEA2
- ProteinIsethionate TRAP transporter permease protein DctMQ
- GenedctMQ
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids635 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Part of the tripartite ATP-independent periplasmic (TRAP) transport system DctPQM involved in the uptake of isethionate (2-hydroxyethanesulfonate), which is then catabolized by enzymes encoded by adjacent genes in the locus. Thereby is involved in an anaerobic respiration pathway that converts the sulfonate isethionate to ammonia, acetate and sulfide.
Pathway
Organosulfur degradation; alkanesulfonate degradation.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | transmembrane transporter activity | |
Biological Process | alkanesulfonate catabolic process |
Keywords
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameIsethionate TRAP transporter permease protein DctMQ
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Thermodesulfobacteriota > Desulfovibrionia > Desulfovibrionales > Desulfovibrionaceae > Oleidesulfovibrio
Accessions
- Primary accessionQ312S1
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 38-58 | Helical | ||||
Sequence: KPFLVAGMLAIIFIITFQTLY | ||||||
Transmembrane | 75-95 | Helical | ||||
Sequence: TEEMARFIFIWISYLAVPVAI | ||||||
Transmembrane | 117-137 | Helical | ||||
Sequence: ISWIIVDVCFLTLAATVLWQS | ||||||
Transmembrane | 154-174 | Helical | ||||
Sequence: LQLPYYIPYLVLPVSFGLMAV | ||||||
Transmembrane | 192-212 | Helical | ||||
Sequence: TVIGLILCAVLAAPLFIADYI | ||||||
Transmembrane | 217-237 | Helical | ||||
Sequence: VLFGYFALFLVVGVPIAIGLG | ||||||
Transmembrane | 266-286 | Helical | ||||
Sequence: FPIMAIPFFIAAGVFMGAGGL | ||||||
Transmembrane | 299-319 | Helical | ||||
Sequence: GALPGGMALATIGTCMFFAAI | ||||||
Transmembrane | 350-370 | Helical | ||||
Sequence: AIVAAAGAIGVMIPPSNPFVV | ||||||
Transmembrane | 379-399 | Helical | ||||
Sequence: IGKLFMGGIVPGLLTGLALMA | ||||||
Transmembrane | 431-451 | Helical | ||||
Sequence: WALMVPVIVLGGIYGGIMTPT | ||||||
Transmembrane | 453-473 | Helical | ||||
Sequence: AAALAAFYGLIIGCFVHRELS | ||||||
Transmembrane | 481-501 | Helical | ||||
Sequence: VVEAAGTSAMVIVLMSMATIF | ||||||
Transmembrane | 526-546 | Helical | ||||
Sequence: IAILLMINVLLLIIGTFMEAL | ||||||
Transmembrane | 572-592 | Helical | ||||
Sequence: IIMVVNLAIGFVTPPVGVNLF | ||||||
Transmembrane | 609-629 | Helical | ||||
Sequence: VLPLIALMLAVLLITTYVPAI |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Cells lacking this gene lose the ability to grow with isethionate as the terminal electron acceptor.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000451053 | 1-635 | Isethionate TRAP transporter permease protein DctMQ | |||
Sequence: MSDPNVTATIMNAQGECSSGSLESRPGILGWLDANFEKPFLVAGMLAIIFIITFQTLYRYIGVYLHEGAAAAVWTEEMARFIFIWISYLAVPVAIKNRSSIRVDIIFDRLPVRFQNISWIIVDVCFLTLAATVLWQSLDLIKMQLTYPQTSPALQLPYYIPYLVLPVSFGLMAVRLLQDLAGQVRICGAADTVIGLILCAVLAAPLFIADYIDPLPVLFGYFALFLVVGVPIAIGLGLAALATIVAAGSLPIDYVAQIAFTSIDSFPIMAIPFFIAAGVFMGAGGLSRRLLNLADEMLGALPGGMALATIGTCMFFAAISGSGPATVAAIGSLTIPAMVERGYCKYFSAAIVAAAGAIGVMIPPSNPFVVYGVSAQASIGKLFMGGIVPGLLTGLALMAYSYWYSKKRGWKGEVRDRNLKTFMHAVWEAKWALMVPVIVLGGIYGGIMTPTEAAALAAFYGLIIGCFVHRELSCGSFYDCVVEAAGTSAMVIVLMSMATIFGNIMTIEEVPTTIAQAMLGLTTDKIAILLMINVLLLIIGTFMEALAAIVILTPILLPIVLKVGVDPVHFGIIMVVNLAIGFVTPPVGVNLFVASGVANAKIEQLSKVVLPLIALMLAVLLITTYVPAIPMFFAG |
Interaction
Subunit
The complex comprises the periplasmic solute receptor protein DctP, and the fused transmembrane protein DctMQ.
Protein-protein interaction databases
Structure
Family & Domains
Sequence similarities
In the N-terminal section; belongs to the TRAP transporter small permease family.
In the C-terminal section; belongs to the TRAP transporter large permease family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length635
- Mass (Da)67,559
- Last updated2005-12-06 v1
- Checksum108A31046282B5D2
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000112 EMBL· GenBank· DDBJ | ABB38075.1 EMBL· GenBank· DDBJ | Genomic DNA |