PKC-ѳ is dispensable for OX40L-induced TCR-independent Treg proliferation but contributes by enabling IL-2 production from effector T-cells.Alharshawi K., Marinelarena A., Kumar P., El-Sayed O., Bhattacharya P., Sun Z., Epstein A.L., Maker A.V., Prabhakar B.S.View abstractCategoriesFunction, InteractionSourceMGI: 103070PubMedEurope PMCSci Rep 7:6594-6594 (2017)Mapped to47
Calmodulin and PI(3,4,5)P(3) cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production.Wang X., Boyken S.E., Hu J., Xu X., Rimer R.P., Shea M.A., Shaw A.S., Andreotti A.H., Huang Y.H.View abstractCategoriesFamily & Domains, InteractionSourceMGI: 103070PubMedEurope PMCSci Signal 7:ra74-ra74 (2014)Mapped to40
Methyltransferase PRMT1 is a binding partner of HBx and a negative regulator of hepatitis B virus transcription.Benhenda S., Ducroux A., Riviere L., Sobhian B., Ward M.D., Dion S., Hantz O., Protzer U., Michel M.L.[...], Neuveut C.View abstractCategoryInteractionSourceMGI: 103070PubMedEurope PMCJ Virol 87:4360-4371 (2013)Mapped to24
Characterization of Ly108 in the thymus: evidence for distinct properties of a novel form of Ly108.Dutta M., Schwartzberg P.L.View abstractCategoriesFunction, PTM / Processing, InteractionSourceMGI: 103070PubMedEurope PMCJ Immunol 188:3031-3041 (2012)Mapped to43
The novel costimulatory programmed death ligand 1/B7.1 pathway is functional in inhibiting alloimmune responses in vivo.Yang J., Riella L.V., Chock S., Liu T., Zhao X., Yuan X., Paterson A.M., Watanabe T., Vanguri V.[...], Sayegh M.H.View abstractCategoryInteractionSourceMGI: 103070PubMedEurope PMCJ Immunol 187:1113-1119 (2011)Mapped to44
The I-A beta b region (65-85) is a binding site for the superantigen, staphylococcal enterotoxin A.Russell J.K., Pontzer C.H., Johnson H.M.View abstractCategoriesSequences, InteractionSourceMGI: 103070PubMedEurope PMCBiochem Biophys Res Commun 168:696-701 (1990)Mapped to24
Promyelocytic leukemia zinc finger turns on the effector T cell program without requirement for agonist TCR signaling.Savage A.K., Constantinides M.G., Bendelac A.View abstractCategoriesFunction, InteractionSourceMGI: 103070PubMedEurope PMCJ Immunol 186:5801-5806 (2011)Mapped to29
Expression of fully assembled TCR-CD3 complex on double positive thymocytes: synergistic role for the PRS and ER retention motifs in the intra-cytoplasmic tail of CD3epsilon.Brodeur J.F., Li S., Damlaj O., Dave V.P.View abstractCategoriesFunction, InteractionSourceMGI: 103070PubMedEurope PMCInt Immunol 21:1317-1327 (2009)Mapped to43
Activated p56lck directs maturation of both CD4 and CD8 single-positive thymocytes.Sohn S.J., Forbush K.A., Pan X.C., Perlmutter R.M.View abstractCategoryInteractionSourceMGI: 103070PubMedEurope PMCJ Immunol 166:2209-2217 (2001)Mapped to27
Enhancement of MHC class I-stimulated alloresponses by TNF/TNF receptor (TNFR)1 interactions and of MHC class II-stimulated alloresponses by TNF/TNFR2 interactions.Brown G.R., Thiele D.L.View abstractCategoryInteractionSourceMGI: 103070PubMedEurope PMCEur J Immunol 30:2900-2907 (2000)Mapped to38