Q30ZJ5 · CHEB2_OLEA2

Function

function

Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site177
Active site203
Active site299

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionphosphorelay response regulator activity
Molecular Functionprotein-glutamate methylesterase activity
Molecular Functionprotein-glutamine glutaminase activity
Biological Processchemotaxis
Biological Processprotein deamination
Biological Processprotein demethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein-glutamate methylesterase/protein-glutamine glutaminase 2
  • EC number

Gene names

    • Name
      cheB2
    • Ordered locus names
      Dde_2104

Organism names

Accessions

  • Primary accession
    Q30ZJ5

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_00002254591-356Protein-glutamate methylesterase/protein-glutamine glutaminase 2
Modified residue574-aspartylphosphate

Post-translational modification

Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

Keywords

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain6-123Response regulatory
Domain165-356CheB-type methylesterase

Domain

Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.

Sequence similarities

Belongs to the CheB family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    356
  • Mass (Da)
    38,050
  • Last updated
    2005-12-06 v1
  • MD5 Checksum
    B2AF41D464059F53173FC0B723F68A83
MARHIKVLIVDDSALVRQTLTDIFSADPELEVVGTASDPFVAVKRMETVVPDVILLDVAMPRMDGLTFLRKIMSQHPIPVVICSAVTEQGAEASFKAMEYGAVEIIQKPKVSTKQFLEESSIRICDAVKAAARAQLRKLAAKRFEVTPKLSADAMLPANAGRSVVQRTEKVVVVGASTGGTEALRVLLEAMPPDCPPIAIVQHMPEHFTAAFAGRLNSTCRIQVKEASDGDVMQRGQALIAPGNLHLLLKRSGSRYYVETKEGPLVRRHRPSVDVLFRSAARYAGNNAVAAIMTGMGDDGAAGMKELHETGAYTIAQDEATCVVYGMPHEAVKLGGVDAVLPLGALAAAIVKACNS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000112
EMBL· GenBank· DDBJ
ABB38901.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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