Q2YRQ4 · FABZ_BRUA2

  • Protein
    3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
  • Gene
    fabZ
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

Features

Showing features for active site.

115720406080100120140
TypeIDPosition(s)Description
Active site58

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Function(3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity
Biological Processfatty acid biosynthetic process
Biological Processlipid A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ
  • EC number
  • Alternative names
    • (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
      ((3R)-hydroxymyristoyl-ACP dehydrase
      )
    • Beta-hydroxyacyl-ACP dehydratase

Gene names

    • Name
      fabZ
    • Ordered locus names
      BAB1_1174

Organism names

  • Taxonomic identifier
  • Strain
    • 2308
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Brucellaceae > Brucella/Ochrobactrum group > Brucella

Accessions

  • Primary accession
    Q2YRQ4
  • Secondary accessions
    • Q44631
    • Q57CY7

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000916501-1573-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the thioester dehydratase family. FabZ subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    157
  • Mass (Da)
    17,214
  • Last updated
    2005-12-20 v1
  • Checksum
    53797D7B16126103
MSDDNQTKLEAADIQALLAVLPHRYPFLLIDRIVDIDGDVSATGIKNVTINEPHFTGHFPENPIMPGVLIVEAMAQTAGAISLLQRKTGRPGVVYFMTIDNAKFRRPVVPGDRLLLYVKKIKQRANISKYECVAEVDGVKVAEAEVAAMISVADENL

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict1-11in Ref. 1

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U51683
EMBL· GenBank· DDBJ
AAA96790.1
EMBL· GenBank· DDBJ
Genomic DNA
AM040264
EMBL· GenBank· DDBJ
CAJ11130.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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