Q2XXQ0 · CRVP_ERYPO

Function

function

Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction. May target voltage-gated calcium channels on smooth muscle (By similarity).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Molecular Functioncalcium channel regulator activity
Molecular Functiontoxin activity

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Cysteine-rich venom protein LIO1
  • Short names
    CRVP
  • Alternative names
    • Cysteine-rich secretory protein LIO1 (CRISP-LIO1)

Organism names

Accessions

  • Primary accession
    Q2XXQ0

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-18
ChainPRO_000038064619-233Cysteine-rich venom protein LIO1
Disulfide bond74↔152
Disulfide bond91↔166
Disulfide bond147↔163
Disulfide bond185↔192
Disulfide bond188↔197
Disulfide bond210↔228
Disulfide bond219↔232

Keywords

Expression

Tissue specificity

Expressed by the venom gland.

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain37-165SCP
Domain201-233ShKT

Sequence similarities

Belongs to the CRISP family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    233
  • Mass (Da)
    26,528
  • Last updated
    2005-12-20 v1
  • Checksum
    B6E9F278123E23DB
MIVFILLSFAAVLQQSFGRIDIDSQSTRRPEIQNLIVDTHNSYRRSVSPTATNMLKMEWYPEAAANAERWAYQCVYDHSQKYERVLDGIQCGENIYMYSEFRPWTEVMQSWYDEYRNFIFGVGAHPANALIGHYTQIVWYKSYRVGCAIANCPSYPYNYFYVCQYCPAGNFGGQTATPYNSGTTCADCPSACDNGLCTNPCTSENVFTNCNDMVKESGCQDERMKSICPASCF

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue233

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ139895
EMBL· GenBank· DDBJ
AAZ75601.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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