Q2XQZ6 · Q2XQZ6_9PSED
- Protein4-hydroxy-2-oxovalerate aldolase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids346 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
Catalytic activity
- (S)-4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate
Features
Showing features for site, binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 16 | Transition state stabilizer | |||
Binding site | 16-17 | substrate | |||
Binding site | 17 | Mn2+ (UniProtKB | ChEBI) | |||
Active site | 20 | Proton acceptor | |||
Binding site | 170 | substrate | |||
Binding site | 199 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 199 | substrate | |||
Binding site | 201 | Mn2+ (UniProtKB | ChEBI) | |||
Binding site | 290 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2-isopropylmalate synthase activity | |
Molecular Function | 4-hydroxy-2-oxovalerate aldolase activity | |
Molecular Function | manganese ion binding | |
Biological Process | catabolic process | |
Biological Process | L-leucine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name4-hydroxy-2-oxovalerate aldolase
- EC number
- Short namesHOA
- Alternative names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas
Accessions
- Primary accessionQ2XQZ6
Structure
Sequence
- Sequence statusComplete
- Length346
- Mass (Da)37,087
- Last updated2005-12-20 v1
- MD5 Checksum8F4EFB0D02A5E0CEACD0C6B65C6E7B40
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
DQ265742 EMBL· GenBank· DDBJ | ABB72213.1 EMBL· GenBank· DDBJ | Genomic DNA |