Q2XQZ6 · Q2XQZ6_9PSED

  • Protein
    4-hydroxy-2-oxovalerate aldolase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

Catalytic activity

Features

Showing features for site, binding site, active site.

134650100150200250300
Type
IDPosition(s)Description
Site16Transition state stabilizer
Binding site16-17substrate
Binding site17Mn2+ (UniProtKB | ChEBI)
Active site20Proton acceptor
Binding site170substrate
Binding site199Mn2+ (UniProtKB | ChEBI)
Binding site199substrate
Binding site201Mn2+ (UniProtKB | ChEBI)
Binding site290substrate

GO annotations

AspectTerm
Molecular Function2-isopropylmalate synthase activity
Molecular Function4-hydroxy-2-oxovalerate aldolase activity
Molecular Functionmanganese ion binding
Biological Processcatabolic process
Biological ProcessL-leucine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-hydroxy-2-oxovalerate aldolase
  • EC number
  • Short names
    HOA
  • Alternative names
    • 4-hydroxy-2-keto-pentanoic acid aldolase
    • 4-hydroxy-2-oxopentanoate aldolase

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • KB35B
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    Q2XQZ6

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain8-260Pyruvate carboxyltransferase

Sequence similarities

Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    346
  • Mass (Da)
    37,087
  • Last updated
    2005-12-20 v1
  • MD5 Checksum
    8F4EFB0D02A5E0CEACD0C6B65C6E7B40
MNLHGKSVILHDMSLRDGMHAKRHQISLEQMVAVATGLDAAGMPLIEITHGDGLGGRSINYGFPAHSDEEYLRAVIPQLKQAKVSALLLPGIGTVEHLRMALDCGVSTIRVATHCTEADVSEQHIGMARKLGVDTVGFLMMAHMISAEKVLEQARLMESYGANCIYCTDSAGYMLPDEVSEKIGLLRAELNPGTEVGFHGHHNMGMAIANSLAAIEAGAARIDGSVAGLGAGAGNTPLEVFVAVCNRMGVETGIDLYKIMDVAEDLVVPMMDQPIRVDRDALTLGYAGVYSSFLLFAQRAEKKYGVSARDILVELGRRGTVGGQEDMIEDLALDMARARQQQKVSA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ265742
EMBL· GenBank· DDBJ
ABB72213.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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