Q2VEG8 · ACCD_SOLTU
- ProteinAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- GeneaccD
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids490 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
Catalytic activity
- acetyl-CoA + N6-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N6-biotinyl-L-lysyl-[protein]
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | acetyl-CoA carboxylase complex | |
Cellular Component | chloroplast stroma | |
Molecular Function | acetyl-CoA carboxylase activity | |
Molecular Function | ATP binding | |
Molecular Function | carboxyl- or carbamoyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | fatty acid biosynthetic process | |
Biological Process | malonyl-CoA biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
- EC number
- Short namesACCase subunit beta ; Acetyl-CoA carboxylase carboxyltransferase subunit beta
Gene names
Encoded on
- Chloroplast
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Solanales > Solanaceae > Solanoideae > Solaneae > Solanum
Accessions
- Primary accessionQ2VEG8
- Secondary accessions
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000277580 | 1-490 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic | |||
Sequence: MERWWFNSMLFKKEFERRCGLNKSMGSLGPIENTSEDPNLKMKNIHSCSNVDYLFGVKDIWNFISDDTFLVSDRNGDSYSIYFDIENQIFEVDNDHSFLSELESSFSSYRNSSYLNNGFRGEDPYYNSYMSYMYDTQYSWNNHINSCIDNYLQSQICIDTSIISGSESYGDSYIYRAICSGESLNSSENEGSSRRTRTKGSDLTIRESSNDLEVTQKYKHLWVQCENCYGLNYKKFLKSKMNICEQCGYHLKMSSSDRIELLIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRIDSYQRKTGLTEAVQTGIGQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEHAANQNLPLIIVCASGGARMQEGSLSLMQMAKISSALYDYQLNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPEGSQAAEYLFQKGLFDLIVPRNLLKSVLSELFKLHAFFPLNQKSSKIK |
Expression
Tissue specificity
RNA expressed in leaf, root, stem, and tuber; the least expression occurs in stems. RNA persists even in senescent leaves.
Induction
Not induced by light.
Interaction
Subunit
Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and 2 subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain, zinc finger.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 184-203 | Disordered | ||||
Sequence: LNSSENEGSSRRTRTKGSDL | ||||||
Domain | 221-490 | CoA carboxyltransferase N-terminal | ||||
Sequence: LWVQCENCYGLNYKKFLKSKMNICEQCGYHLKMSSSDRIELLIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRIDSYQRKTGLTEAVQTGIGQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEHAANQNLPLIIVCASGGARMQEGSLSLMQMAKISSALYDYQLNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPEGSQAAEYLFQKGLFDLIVPRNLLKSVLSELFKLHAFFPLNQKSSKIK | ||||||
Zinc finger | 225-247 | C4-type | ||||
Sequence: CENCYGLNYKKFLKSKMNICEQC |
Sequence similarities
Belongs to the AccD/PCCB family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length490
- Mass (Da)55,596
- Last updated2009-01-20 v3
- ChecksumDFD4751300F86C5B
Sequence caution
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 399 | in Ref. 2; ABB90050 | ||||
Sequence: T → K |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF069288 EMBL· GenBank· DDBJ | AAC23997.1 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation | |
DQ231562 EMBL· GenBank· DDBJ | ABB90050.1 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation | |
DQ386163 EMBL· GenBank· DDBJ | ABD47066.1 EMBL· GenBank· DDBJ | Genomic DNA | Different initiation |