Q2VEG8 · ACCD_SOLTU

  • Protein
    Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
  • Gene
    accD
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    4/5

Function

function

Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site225Zn2+ (UniProtKB | ChEBI)
Binding site228Zn2+ (UniProtKB | ChEBI)
Binding site244Zn2+ (UniProtKB | ChEBI)
Binding site247Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentacetyl-CoA carboxylase complex
Cellular Componentchloroplast stroma
Molecular Functionacetyl-CoA carboxylase activity
Molecular FunctionATP binding
Molecular Functioncarboxyl- or carbamoyltransferase activity
Molecular Functionzinc ion binding
Biological Processfatty acid biosynthetic process
Biological Processmalonyl-CoA biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic
  • EC number
  • Short names
    ACCase subunit beta
    ; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Gene names

    • Name
      accD

Encoded on

  • Chloroplast

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Desiree
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Solanales > Solanaceae > Solanoideae > Solaneae > Solanum

Accessions

  • Primary accession
    Q2VEG8
  • Secondary accessions
    • O78323

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002775801-490Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic

Expression

Tissue specificity

RNA expressed in leaf, root, stem, and tuber; the least expression occurs in stems. RNA persists even in senescent leaves.

Induction

Not induced by light.

Interaction

Subunit

Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein, biotin carboxylase and 2 subunits each of ACCase subunit alpha and ACCase plastid-coded subunit beta (accD).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain, zinc finger.

TypeIDPosition(s)Description
Region184-203Disordered
Domain221-490CoA carboxyltransferase N-terminal
Zinc finger225-247C4-type

Sequence similarities

Belongs to the AccD/PCCB family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    490
  • Mass (Da)
    55,596
  • Last updated
    2009-01-20 v3
  • Checksum
    DFD4751300F86C5B
MERWWFNSMLFKKEFERRCGLNKSMGSLGPIENTSEDPNLKMKNIHSCSNVDYLFGVKDIWNFISDDTFLVSDRNGDSYSIYFDIENQIFEVDNDHSFLSELESSFSSYRNSSYLNNGFRGEDPYYNSYMSYMYDTQYSWNNHINSCIDNYLQSQICIDTSIISGSESYGDSYIYRAICSGESLNSSENEGSSRRTRTKGSDLTIRESSNDLEVTQKYKHLWVQCENCYGLNYKKFLKSKMNICEQCGYHLKMSSSDRIELLIDPGTWDPMDEDMVSLDPIEFHSEEEPYKDRIDSYQRKTGLTEAVQTGIGQLNGIPVAIGVMDFQFMGGSMGSVVGEKITRLIEHAANQNLPLIIVCASGGARMQEGSLSLMQMAKISSALYDYQLNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPEGSQAAEYLFQKGLFDLIVPRNLLKSVLSELFKLHAFFPLNQKSSKIK

Sequence caution

The sequence AAC23997.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.
The sequence ABB90050.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.
The sequence ABD47066.1 differs from that shown. Reason: Erroneous initiation Extended N-terminus.

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict399in Ref. 2; ABB90050

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF069288
EMBL· GenBank· DDBJ
AAC23997.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation
DQ231562
EMBL· GenBank· DDBJ
ABB90050.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation
DQ386163
EMBL· GenBank· DDBJ
ABD47066.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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