Q2UKD0 · XYL1_ASPOR

Function

function

Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).

Catalytic activity

Pathway

Carbohydrate metabolism; D-xylose degradation.

Features

Showing features for active site, site, binding site.

Type
IDPosition(s)Description
Active site50Proton donor
Site79Lowers pKa of active site Tyr
Binding site112substrate
Binding site166-167NAD+ (UniProtKB | ChEBI)
Binding site215-224NAD+ (UniProtKB | ChEBI)
Binding site271-281NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentextracellular region
Molecular FunctionD-xylose reductase (NADPH) activity
Biological ProcessD-xylose catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable NAD(P)H-dependent D-xylose reductase xyl1
  • EC number
  • Short names
    XR

Gene names

    • Name
      xyl1
    • Synonyms
      XR
    • ORF names
      AO090003000859

Organism names

Accessions

  • Primary accession
    Q2UKD0

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003935011-319Probable NAD(P)H-dependent D-xylose reductase xyl1

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the aldo/keto reductase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    319
  • Mass (Da)
    35,868
  • Last updated
    2006-01-24 v1
  • Checksum
    348BB434877572C2
MASPTVKLNSGHDMPLVGFGLWKVNNETCADQVYEAIKAGYRLFDGACDYGNEVECGQGVARAIKEGIVKREELFIVSKLWNSFHEGDRVEPICRKQLADWGVDYFDLYIVHFPVALKYVDPAVRYPPGWNSESGKIEFSNATIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYARVRPATLQIEHHPYLTQPRLVEYAQKEGIAVTAYSSFGPLSFLELEVKNAVDTPPLFEHNTIKSLAEKYGKTPAQVLLRWATQRGIAVIPKSNNPTRLSQNLEVTGWDLEKSELEAISSLDKGLRFNDPIGYGMYVPIF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FJ957890
EMBL· GenBank· DDBJ
ACX46082.1
EMBL· GenBank· DDBJ
Genomic DNA
FJ957891
EMBL· GenBank· DDBJ
ACX46083.1
EMBL· GenBank· DDBJ
Genomic DNA
BA000050
EMBL· GenBank· DDBJ
BAE57985.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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