Q2UH11 · MOCOS_ASPOR
- ProteinMolybdenum cofactor sulfurase
- GenehxB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids822 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
Catalytic activity
- Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Cofactor
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 401 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | lyase activity | |
Molecular Function | Mo-molybdopterin cofactor sulfurase activity | |
Molecular Function | molybdenum cofactor sulfurtransferase activity | |
Molecular Function | molybdenum ion binding | |
Molecular Function | pyridoxal phosphate binding | |
Biological Process | Mo-molybdopterin cofactor biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMolybdenum cofactor sulfurase
- EC number
- Short namesMCS ; MOS ; MoCo sulfurase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Circumdati
Accessions
- Primary accessionQ2UH11
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000249962 | 1-822 | Molybdenum cofactor sulfurase | ||
Modified residue | 239 | N6-(pyridoxal phosphate)lysine | |||
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 633-648 | Polar residues | |||
Region | 633-666 | Disordered | |||
Domain | 643-820 | MOSC | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length822
- Mass (Da)91,162
- Last updated2013-10-16 v2
- Checksum846EF95DC0255FFB
Sequence caution
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 633-648 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000051 EMBL· GenBank· DDBJ | BAE59154.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. |