Q2TPW5 · JUGR4_JUGRE
- Protein11S globulin seed storage protein Jug r 4
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids507 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Seed storage protein.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | IgE binding | |
Molecular Function | nutrient reservoir activity | |
Biological Process | seed development |
Keywords
- Molecular function
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended name11S globulin seed storage protein Jug r 4
- Cleaved into 2 chains
- Allergen nameJug r 4
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > fabids > Fagales > Juglandaceae > Juglans
Accessions
- Primary accessionQ2TPW5
Proteomes
Genome annotation databases
Phenotypes & Variants
Allergenic properties
Causes an allergic reaction in human. Binds to IgE.
Keywords
- Disease
Protein family/group databases
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-23 | |||||
Sequence: MAKPILLSIYLFLIVALFNGCLA | ||||||
Chain | PRO_0000446017 | 24-315 | 11S globulin seed storage protein Jug r 4 acidic chain | |||
Sequence: QSGGRQQQQFGQCQLNRLDALEPTNRIEAEAGVIESWDPNNQQFQCAGVAVVRRTIEPNGLLLPQYSNAPQLVYIARGRGITGVLFPGCPETFEESQRQSQQGQSREFQQDRHQKIRHFREGDIIAFPAGVAHWSYNDGSNPVVAISLLDTNNNANQLDQNPRNFYLAGNPDDEFRPQGQQEYEQHRRQQQRQQRPGEHGQQQRGLGNNVFSGFDADFLADAFNVDTETARRLQSENDHRRSIVRVEGRQLQVIRPRWSREEQEREERKERERERESESERRQSRRGGRDDN | ||||||
Disulfide bond | 36↔69 | |||||
Sequence: CQLNRLDALEPTNRIEAEAGVIESWDPNNQQFQC | ||||||
Disulfide bond | 112↔322 | Interchain (between acidic and basic chains) | ||||
Sequence: CPETFEESQRQSQQGQSREFQQDRHQKIRHFREGDIIAFPAGVAHWSYNDGSNPVVAISLLDTNNNANQLDQNPRNFYLAGNPDDEFRPQGQQEYEQHRRQQQRQQRPGEHGQQQRGLGNNVFSGFDADFLADAFNVDTETARRLQSENDHRRSIVRVEGRQLQVIRPRWSREEQEREERKERERERESESERRQSRRGGRDDNGLEETIC | ||||||
Chain | PRO_0000446018 | 316-507 | 11S globulin seed storage protein Jug r 4 basic chain | |||
Sequence: GLEETICTLRLRENIGDPSRADIYTEEAGRISTVNSHTLPVLRWLQLSAERGALYSDALYVPHWNLNAHSVVYALRGRAEVQVVDNFGQTVFDDELREGQLLTIPQNFAVVKRARNEGFEWVSFKTNENAMVSPLAGRTSAIRALPEEVLATAFQIPREDARRLKFNRQESTLVRSRPSRSRSSRSERRAEV |
Post-translational modification
Proteolytically processed from a single precursor to produce an acidic and a basic chain that are linked by a disulfide bond.
Keywords
- PTM
Expression
Tissue specificity
Expressed in seeds.
Developmental stage
Expressed during seed development.
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, domain, compositional bias, motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-15 | IgE-binding | ||||
Sequence: MAKPILLSIYLFLIV | ||||||
Domain | 41-254 | Cupin type-1 1 | ||||
Sequence: LDALEPTNRIEAEAGVIESWDPNNQQFQCAGVAVVRRTIEPNGLLLPQYSNAPQLVYIARGRGITGVLFPGCPETFEESQRQSQQGQSREFQQDRHQKIRHFREGDIIAFPAGVAHWSYNDGSNPVVAISLLDTNNNANQLDQNPRNFYLAGNPDDEFRPQGQQEYEQHRRQQQRQQRPGEHGQQQRGLGNNVFSGFDADFLADAFNVDTETAR | ||||||
Region | 57-71 | IgE-binding | ||||
Sequence: IESWDPNNQQFQCAG | ||||||
Region | 89-103 | IgE-binding | ||||
Sequence: YSNAPQLVYIARGRG | ||||||
Region | 105-119 | IgE-binding | ||||
Sequence: TGVLFPGCPETFEES | ||||||
Region | 121-143 | IgE-binding | ||||
Sequence: RQSQQGQSREFQQDRHQKIRHFR | ||||||
Region | 145-159 | IgE-binding | ||||
Sequence: GDIIAFPAGVAHWSY | ||||||
Region | 191-233 | Disordered | ||||
Sequence: AGNPDDEFRPQGQQEYEQHRRQQQRQQRPGEHGQQQRGLGNNV | ||||||
Compositional bias | 200-217 | Basic and acidic residues | ||||
Sequence: PQGQQEYEQHRRQQQRQQ | ||||||
Region | 201-223 | IgE-binding | ||||
Sequence: QGQQEYEQHRRQQQRQQRPGEHG | ||||||
Compositional bias | 218-232 | Polar residues | ||||
Sequence: RPGEHGQQQRGLGNN | ||||||
Region | 233-247 | IgE-binding | ||||
Sequence: VFSGFDADFLADAFN | ||||||
Region | 257-295 | IgE-binding | ||||
Sequence: QSENDHRRSIVRVEGRQLQVIRPRWSREEQEREERKERE | ||||||
Region | 281-316 | Disordered | ||||
Sequence: WSREEQEREERKERERERESESERRQSRRGGRDDNG | ||||||
Region | 313-327 | IgE-binding | ||||
Sequence: DDNGLEETICTLRLR | ||||||
Motif | 315-320 | NGXEET; peptidase recognition motif | ||||
Sequence: NGLEET | ||||||
Domain | 328-477 | Cupin type-1 2 | ||||
Sequence: ENIGDPSRADIYTEEAGRISTVNSHTLPVLRWLQLSAERGALYSDALYVPHWNLNAHSVVYALRGRAEVQVVDNFGQTVFDDELREGQLLTIPQNFAVVKRARNEGFEWVSFKTNENAMVSPLAGRTSAIRALPEEVLATAFQIPREDAR | ||||||
Region | 377-399 | IgE-binding | ||||
Sequence: PHWNLNAHSVVYALRGRAEVQVV | ||||||
Region | 417-439 | IgE-binding | ||||
Sequence: LTIPQNFAVVKRARNEGFEWVSF | ||||||
Region | 465-479 | IgE-binding | ||||
Sequence: LATAFQIPREDARRL | ||||||
Region | 481-503 | IgE-binding | ||||
Sequence: FNRQESTLVRSRPSRSRSSRSER | ||||||
Region | 484-507 | Disordered | ||||
Sequence: QESTLVRSRPSRSRSSRSERRAEV |
Sequence similarities
Belongs to the 11S seed storage protein (globulins) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length507
- Mass (Da)58,144
- Last updated2006-01-24 v1
- ChecksumC587BAB906711472
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 200-217 | Basic and acidic residues | ||||
Sequence: PQGQQEYEQHRRQQQRQQ | ||||||
Compositional bias | 218-232 | Polar residues | ||||
Sequence: RPGEHGQQQRGLGNN |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY692446 EMBL· GenBank· DDBJ | AAW29810.1 EMBL· GenBank· DDBJ | mRNA |