Essential maintenance is planned to begin on Tue Jan 28 2025. The website may be temporarily unavailable. Please use our fallback: https://wwwdev.ebi.ac.uk/uniprot/front-end/fallback/ during this time.

Q2T9T0 · SAXO4_BOVIN

  • Protein
    Stabilizer of axonemal microtubules 4
  • Gene
    SAXO4
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentaxonemal A tubule inner sheath
Cellular Componentcilium
Cellular Componentcytoplasm
Cellular Componentsperm flagellum
Molecular Functionphosphatase binding
Biological Processflagellated sperm motility

Names & Taxonomy

Protein names

  • Recommended name
    Stabilizer of axonemal microtubules 4
  • Alternative names
    • Protein phosphatase 1 regulatory subunit 32

Gene names

    • Name
      SAXO4
    • Synonyms
      PPP1R32

Organism names

  • Taxonomic identifier
  • Strain
    • Crossbred X Angus
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    Q2T9T0

Proteomes

Subcellular Location

Cytoplasm
Note: Localized to the cilia of polarized ependymal cells during development and at the adult stage. Preferentially locates between the peripheral microtubules of the axoneme and the ciliary membrane.

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002743761-428Stabilizer of axonemal microtubules 4

Proteomic databases

Interaction

Subunit

Microtubule inner protein component of sperm flagellar doublet microtubules (PubMed:37327785).
Interacts with PPP1CA (By similarity).

Protein-protein interaction databases

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias201-219Polar residues
Region201-231Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    428
  • Mass (Da)
    47,759
  • Last updated
    2006-01-24 v1
  • MD5 Checksum
    3C9A150DBD7FD1FE8D2C4AA50C917435
MMGKLPLGVVSPYVKMSSGGCTDPLKFYATSYCTAYGREDFKPRVGSHRGTGYKSNYRPVVFYQPHLDALDNTATGEQGCNNFQTVTSQSYRPLEVPDGTHPLPWNLHQTNSGYSREKASAVTPIKEVRKVHFDTQDYGPQAITGLEPKDAPLLHQQQNKGSLEWENAGHGPRFMTSEYNSKYLKEPSHQPDLLQKNSVGAKEETGFTEESNKNPIVFQPPSQALPGDPVLLPGRSVTKSDFLPISHPHGDEFLPVLARGSERETGFSRVNERTLNPRVPPPCPEPSSMNHWQFQSPQRMQQTNVALLGRETVGNKEPSGFSLNNPSYVRSPYDPDMDNRYLTTYNQGYFENIPKGLDREGWTRGGLQPQKPGGYALNQPVTRLEATPTPTESLRRLHPHLGRTLISVDPFYRTAPPSGHVSRFTAPN

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias201-219Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC111283
EMBL· GenBank· DDBJ
AAI11284.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help