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Q2RTC3 · Q2RTC3_RHORT

Function

function

Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

Catalytic activity

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.

Features

Showing features for binding site, active site.

115320406080100120140
Type
IDPosition(s)Description
Binding site165-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site47-495-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site78-805-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site83-84(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)
Active site86Proton donor
Binding site1115-amino-6-(D-ribitylamino)uracil (UniProtKB | ChEBI)
Binding site125(2S)-2-hydroxy-3-oxobutyl phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentriboflavin synthase complex
Molecular Function6,7-dimethyl-8-ribityllumazine synthase activity
Biological Processriboflavin biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    6,7-dimethyl-8-ribityllumazine synthase
  • EC number
  • Short names
    DMRL synthase
    ; LS
    ; Lumazine synthase

Gene names

    • Name
      ribH
    • Ordered locus names
      Rru_A1822

Organism names

Accessions

  • Primary accession
    Q2RTC3

Proteomes

Subcellular Location

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the DMRL synthase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    153
  • Mass (Da)
    16,498
  • Last updated
    2006-01-24 v1
  • MD5 Checksum
    407091FC78CB65C76220A5920EC77C8C
MSTTGGPRILIVEARFYEEITDNLVRGAVQALTAAGAGFKRIIVPGIIETPAVIRYAVRSIELRATDHRYAGYVVLGCAIKGETDHYENAARVAMDGIKDLTLQYSLAVGNGILTCRTGEQALVRSDPAGRDFGGQAARACLRMLDVKREMGL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000230
EMBL· GenBank· DDBJ
ABC22622.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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