Q2RL24 · NTPPA_MOOTA
- ProteindTTP/UTP pyrophosphatase
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids194 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Catalytic activity
- dTTP + H2O = dTMP + diphosphate + H+
Cofactor
Features
Showing features for site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 12 | Important for substrate specificity | |||
Active site | 69 | Proton acceptor | |||
Site | 70 | Important for substrate specificity | |||
Site | 154 | Important for substrate specificity | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | dTTP diphosphatase activity | |
Molecular Function | UTP diphosphatase activity | |
Biological Process | nucleotide metabolic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namedTTP/UTP pyrophosphatase
- EC number
- Short namesdTTPase/UTPase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacillota > Clostridia > Moorellales > Moorellaceae > Moorella
Accessions
- Primary accessionQ2RL24
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000267343 | 1-194 | dTTP/UTP pyrophosphatase | ||
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length194
- Mass (Da)20,427
- Last updated2006-01-24 v1
- ChecksumC3E3272C17433E22
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP000232 EMBL· GenBank· DDBJ | ABC18865.1 EMBL· GenBank· DDBJ | Genomic DNA |