Q2PYM7 · Q2PYM7_PIG

  • Protein
    Proteasome subunit beta
  • Gene
    PSMB9
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Catalytic activity

  • Cleavage of peptide bonds with very broad specificity.
    EC:3.4.25.1 (UniProtKB | ENZYME | Rhea)

Features

Showing features for active site.

121920406080100120140160180200
TypeIDPosition(s)Description
Active site21Nucleophile

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentnucleus
Cellular Componentproteasome core complex, beta-subunit complex
Molecular Functionendopeptidase activity
Molecular Functionthreonine-type endopeptidase activity
Biological Processproteasome-mediated ubiquitin-dependent protein catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Proteasome subunit beta

Gene names

    • Name
      PSMB9
    • Synonyms
      LMP2
    • ORF names
      SBAB-554F3.3-001

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Duroc
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Suina > Suidae > Sus

Accessions

  • Primary accession
    Q2PYM7
  • Secondary accessions
    • A0A4X1V0J8

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

Component of the proteasome complex.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the peptidase T1B family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    219
  • Mass (Da)
    23,330
  • Last updated
    2006-01-24 v1
  • Checksum
    22F6F22976A6D6FB
MLRAGGPTGDLPRAGEVHTGTTIMAVEFDGGVVVGSDSRVSAGEAVVNRVFDKLSPLHHRIYCALSGSAADAQAIADMAAYQLELHGMELEEPPLVLAAANVVRNISYKYREDLSAHLMVAGWDQREGGQVYGTMGGMLIRQPFAIGGSGSTYIYGYVDAAYKPGMSPEECRRFTTNAIALAMNRDGSSGGVIYLVTITAAGVDHRVILGNELPKFYDE

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A8W4FBJ6A0A8W4FBJ6_PIGPSMB9170
A5D9J1A5D9J1_PIGPSMB9175
A0A5G2R095A0A5G2R095_PIGPSMB9170

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ295031
EMBL· GenBank· DDBJ
ABC02872.1
EMBL· GenBank· DDBJ
mRNA
DQ333333
EMBL· GenBank· DDBJ
ABC59113.1
EMBL· GenBank· DDBJ
mRNA
DQ659151
EMBL· GenBank· DDBJ
ABG57117.1
EMBL· GenBank· DDBJ
Genomic DNA
BX323833
EMBL· GenBank· DDBJ
CAN13314.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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