Q2PBM3 · LSRA_PHOTE

  • Protein
    Autoinducer 2 import ATP-binding protein LsrA
  • Gene
    lsrA
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Responsible for energy coupling to the transport system.

Catalytic activity

  • ATP + H2O + (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran-[AI-2-binding protein]Side 1 = ADP + phosphate + (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuranSide 2 + [AI-2-binding protein]Side 1.
    EC:7.6.2.13 (UniProtKB | ENZYME | Rhea)

Features

Showing features for binding site.

152050100150200250300350400450500
TypeIDPosition(s)Description
Binding site44-51ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Autoinducer 2 import ATP-binding protein LsrA
  • EC number
  • Short names
    AI-2 import ATP-binding protein LsrA

Gene names

    • Name
      lsrA

Organism names

  • Taxonomic identifier
  • Strain
    • C1 / NC19
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Photorhabdus

Accessions

  • Primary accession
    Q2PBM3

Subcellular Location

Cell inner membrane
; Peripheral membrane protein

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003512991-520Autoinducer 2 import ATP-binding protein LsrA

Interaction

Subunit

The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain12-240ABC transporter 1
Domain264-503ABC transporter 2

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    520
  • Mass (Da)
    57,213
  • Last updated
    2006-02-07 v1
  • Checksum
    A04ED2E6FF62F126
MLHNNTAVPPLLEVSGISKQFSGVMVLKHIDFTLLPGQIHALLGGNGAGKSTLMKIIAGIEQPDKGSIKIDGNNVSHLNPTKAHQLGIYLIPQEPLLFPNLSVQENILFRLPKHQADKARMKHLLELLGCQLDLNANAGSLNVADQQLVEVMRGLIRNSNVLILDEPTASLTPAETERLFTQLRELQQQSVGIIFISHKIPEIHQLADQVSVMRDGGIALSGKTCDYTTDDIIRAITPAAKNKPLTDTEKRWSELNDNPQKTSSDLPVLTVTDLNGEGFRNITLSVKPGEILGLAGVVGAGRTELAETLYGLRPVLSGEIKLKQCPITRLKTVQRLKQGLVYLPEDRQSSGLFPDSSLSWNICSLTHNNRTFWVHPTYDATVVERYRQALNIKFSHINQPVKTLSGGNQQKILIAKCLEAHPAVLIIDEPTRGVDIAARNDIYQLIHNIAQQQVAIIFISSDLDEVVQMADRVLVMHQGEINGELTKQQIDVDTIMHIAFGEHKSQQAVSTIKTDKAASC

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ967009
EMBL· GenBank· DDBJ
CAI91185.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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