The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]TissuePCR rescued clonesCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Galpha12 and Galpha13 mediate differentiation of P19 mouse embryonal carcinoma cells in response to retinoic acid.Jho E.H., Malbon C.C.View abstractCategoriesFunction, InteractionSourceMGI: 95767PubMedEurope PMCJ Biol Chem 272:24461-24467 (1997)Mapped to8
Vascular system defects and impaired cell chemokinesis as a result of Galpha13 deficiency.Offermanns S., Mancino V., Revel J.P., Simon M.I.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCScience 275:533-536 (1997)Mapped to14
G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.Williams C.J., Schultz R.M., Kopf G.S.View abstractCategorySequencesSourceMGI: 95767PubMedEurope PMCMol. Reprod. Dev. 44:315-323 (1996)Cited in111Mapped to99+
Analysis of G protein alpha subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach.Rambhatla L., Patel B., Dhanasekaran N., Latham K.E.View abstractCategorySequencesSourceMGI: 95767PubMedEurope PMCMol Reprod Dev 41:314-324 (1995)Mapped to51
Structural features of the murine gene encoding the RI beta subunit of cAMP-dependent protein kinase.Clegg C.H., Koeiman N.R., Jenkins N.A., Gilbert D.J., Copeland N.G., Neubauer M.G.View abstractCategorySequencesSourceMGI: 95767PubMedEurope PMCMol Cell Neurosci 5:153-164 (1994)Mapped to31
Dual regulation of NEMO by Nrf2 and miR-125a inhibits ferroptosis and protects liver from endoplasmic reticulum stress-induced injury.Tak J., Joo M.S., Kim Y.S., Park H.W., Lee C.H., Park G.C., Hwang S., Kim S.G.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCTheranostics 14:1841-1859 (2024)Mapped to15
Galphapisub>12pi/sub> overexpression in hepatocytes by ER stress exacerbates acute liver injury via ROCK1-mediated miR-15a and ALOX12 dysregulation.Tak J., Kim Y.S., Kim T.H., Park G.C., Hwang S., Kim S.G.View abstractCategoriesFunction, ExpressionSourceMGI: 95767PubMedEurope PMCTheranostics 12:1570-1588 (2022)Mapped to3
Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis.van den Bos E., Ambrosy B., Horsthemke M., Walbaum S., Bachg A.C., Wettschureck N., Innamorati G., Wilkie T.M., Hanley P.J.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCJ Biol Chem 295:7726-7742 (2020)Mapped to41
Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of Its Interaction With Actin.Sakaguchi T., Takefuji M., Wettschureck N., Hamaguchi T., Amano M., Kato K., Tsuda T., Eguchi S., Ishihama S.[...], Murohara T.View abstractCategoriesFunction, PTM / ProcessingSourceMGI: 95767PubMedEurope PMCCirculation 140:1737-1752 (2019)Mapped to19
Myogenic vasoconstriction requires Gpisub>12pi/sub>/Gpisub>13pi/sub> and LARG to maintain local and systemic vascular resistance.Chennupati R., Wirth A., Favre J., Li R., Bonnavion R., Jin Y.J., Wietelmann A., Schweda F., Wettschureck N.[...], Offermanns S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 95767PubMedEurope PMCElife 8:e49374-e49374 (2019)Mapped to20
Translating biased signaling in the ghrelin receptor system into differential in vivo functions.Mende F., Hundahl C., Plouffe B., Skov L.J., Sivertsen B., Madsen A.N., Luckmann M., Diep T.A., Offermanns S.[...], Holst B.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCProc Natl Acad Sci U S A 115:E10255-E10264 (2018)Mapped to18
Galpha12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration.Kim T.H., Yang Y.M., Han C.Y., Koo J.H., Oh H., Kim S.S., You B.H., Choi Y.H., Park T.S.[...], Kim S.G.View abstractCategoriesFunction, InteractionSourceMGI: 95767PubMedEurope PMCJ Clin Invest 128:5587-5602 (2018)Mapped to13
Balance of Go1alpha and Go2alpha expression regulates motor function via the striatal dopaminergic system.Baron J., Bilbao A., Hortnagl H., Birnbaumer L., Leixner S., Spanagel R., Ahnert-Hilger G., Brunk I.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCJ Neurochem 146:374-389 (2018)Mapped to13
Novel Adipokine, FAM19A5, Inhibits Neointima Formation After Injury Through Sphingosine-1-Phosphate Receptor 2.Wang Y., Chen D., Zhang Y., Wang P., Zheng C., Zhang S., Yu B., Zhang L., Zhao G.[...], Kong W.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCCirculation 138:48-63 (2018)Cited in5Mapped to37
Loss of epithelial Gq and G11 signaling inhibits TGFbeta production but promotes IL-33-mediated macrophage polarization and emphysema.John A.E., Wilson M.R., Habgood A., Porte J., Tatler A.L., Stavrou A., Miele G., Jolly L., Knox A.J.[...], Jenkins R.G.View abstractCategoriesFunction, Subcellular LocationSourceMGI: 95767PubMedEurope PMCSci Signal 9:ra104-ra104 (2016)Mapped to22
Galpha12 is required for renal cystogenesis induced by Pkd1 inactivation.Wu Y., Xu J.X., El-Jouni W., Lu T., Li S., Wang Q., Tran M., Yu W., Wu M.[...], Kong T.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCJ Cell Sci 129:3675-3684 (2016)Mapped to16
Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways.Xiang X., Li S., Zhuang X., Shi L.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCFEBS Lett 590:2940-2955 (2016)Mapped to27
S1P2/G12/13 Signaling Negatively Regulates Macrophage Activation and Indirectly Shapes the Atheroprotective B1-Cell Population.Grimm M., Tischner D., Troidl K., Albarran Juarez J., Sivaraj K.K., Ferreiros Bouzas N., Geisslinger G., Binder C.J., Wettschureck N.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCArterioscler Thromb Vasc Biol 36:37-48 (2016)Mapped to10
Age-dependent blood pressure elevation is due to increased vascular smooth muscle tone mediated by G-protein signalling.Wirth A., Wang S., Takefuji M., Tang C., Althoff T.F., Schweda F., Wettschureck N., Offermanns S.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCCardiovasc Res 109:131-140 (2016)Mapped to48
Kidney injury molecule-1 protects against Galpha12 activation and tissue damage in renal ischemia-reperfusion injury.Ismail O.Z., Zhang X., Wei J., Haig A., Denker B.M., Suri R.S., Sener A., Gunaratnam L.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCAm J Pathol 185:1207-1215 (2015)Mapped to7
The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Galpha12/13 and RhoA.Ackerman S.D., Garcia C., Piao X., Gutmann D.H., Monk K.R.View abstractCategoriesFunction, ExpressionSourceMGI: 95767PubMedEurope PMCNat Commun 6:6122-6122 (2015)Cited in2Mapped to22
Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse.Strathmann M., Wilkie T.M., Simon M.I.View abstractCategorySequencesSourceMGI: 95767PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 86:7407-7409 (1989)Cited in5Mapped to74
Galpha12 gep oncogene deregulation of p53-responsive microRNAs promotes epithelial-mesenchymal transition of hepatocellular carcinoma.Yang Y.M., Lee W.H., Lee C.G., An J., Kim E.S., Kim S.H., Lee S.K., Lee C.H., Dhanasekaran D.N.[...], Kim S.G.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCOncogene 34:2910-2921 (2015)Mapped to7
G-protein stimulatory subunit alpha and Gq/11alpha G-proteins are both required to maintain quiescent stem-like chondrocytes.Chagin A.S., Vuppalapati K.K., Kobayashi T., Guo J., Hirai T., Chen M., Offermanns S., Weinstein L.S., Kronenberg H.M.View abstractCategoryFunctionSourceMGI: 95767PubMedEurope PMCNat Commun 5:3673-3673 (2014)Mapped to32