Q2NA81 · COAX_ERYLH

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Catalytic activity

Cofactor

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

125920406080100120140160180200220240
Type
IDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site108-111substrate
Active site110Proton acceptor
Binding site130K+ (UniProtKB | ChEBI)
Binding site133ATP (UniProtKB | ChEBI)
Binding site187substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • Ordered locus names
      ELI_06590

Organism names

Accessions

  • Primary accession
    Q2NA81

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_10000543761-259Type III pantothenate kinase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    259
  • Mass (Da)
    28,086
  • Last updated
    2006-02-07 v1
  • Checksum
    D8F9D875F06E613F
MLLAADVGNTNVVFALFEGRDIRARWRIATDPRRTGDEYAVWLLQLLQIEGVQREEITQIIFASVVPRANHNLTVLCEKYFGIAPLVAGEGKAAWPFQADVDQPSSLGADRALNILAAHEKYGGDLIVVDFGTATKLEAIDFNGTYKGGIIAPGINLSLDALVGKTAKLPRIAIRAPETASVIGRNTEDQMLIGVFWAHVAMMEGLIERMRAEIGRPAKVVATGGLAILFDEKTDIFDHVDADLTIEGLAILAEHASKQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000157
EMBL· GenBank· DDBJ
ABC63410.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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