Q2N5Q5 · RPOC_ERYLH

Function

function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site70Zn2+ 1 (UniProtKB | ChEBI)
Binding site72Zn2+ 1 (UniProtKB | ChEBI)
Binding site85Zn2+ 1 (UniProtKB | ChEBI)
Binding site88Zn2+ 1 (UniProtKB | ChEBI)
Binding site461Mg2+ (UniProtKB | ChEBI)
Binding site463Mg2+ (UniProtKB | ChEBI)
Binding site465Mg2+ (UniProtKB | ChEBI)
Binding site821Zn2+ 2 (UniProtKB | ChEBI)
Binding site895Zn2+ 2 (UniProtKB | ChEBI)
Binding site902Zn2+ 2 (UniProtKB | ChEBI)
Binding site905Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentDNA-directed RNA polymerase complex
Molecular FunctionDNA binding
Molecular FunctionDNA-directed 5'-3' RNA polymerase activity
Molecular Functionmagnesium ion binding
Molecular Functionzinc ion binding
Biological ProcessDNA-templated transcription

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    DNA-directed RNA polymerase subunit beta'
  • EC number
  • Short names
    RNAP subunit beta'
  • Alternative names
    • RNA polymerase subunit beta'
    • Transcriptase subunit beta'

Gene names

    • Name
      rpoC
    • Ordered locus names
      ELI_14470

Organism names

Accessions

  • Primary accession
    Q2N5Q5

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003533541-1438DNA-directed RNA polymerase subunit beta'

Interaction

Subunit

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1413-1438Disordered

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,438
  • Mass (Da)
    159,738
  • Last updated
    2006-02-07 v1
  • Checksum
    E6251C98C4E68B5C
MNELTKFTNQLAKPETFDQIQIGIASPERIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRMKYKGVVCEKCGVEVTVTKVRRERMGHIELAAPVAHIWFLKSLPSRIGLLLDMQLKQLERVLYFEHYIVTEPGLTPLEKFQLLTEDELLEAQDEYGEDAFSAGIGAEAVKFMLMDLDLEQEKEDLLEELATTKSKLKPAKIIKRLKVVESFIESGNRPEWMILEVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYARLDAKGLSMTLKQAKKWVEKERKEVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILSPANGKPIIVPSQDMVLGLYYLSMERQEKTPEYIEEKDGTKIEKLPRFADMAEVHQALETKSVTLHTRIIARVPQADEDGKPEMKRFVTTPGRMLIGECLPKNHKVPYDIVNRLLTKKEIGDVIDQVYRHTGQKDTVLFADAIMVLGFRHAFKAGISFGKDDMIIPDSKEGMIEDTKKQVADYEQQYQDGLITQQEKYNKVIDAWSRCGDQVAEAMMDEIKSQKFDKDGKESEINSIYMMSHSGARGSPAQMKQLAGMRGLMAKPSGEIIENPIISNFKEGLTVLEYFNSTHGARKGLADTALKTANSGYLTRRLVDVSQDCVIVEEDCKTDNALEMRAIVQGGSVIASLGERILGRTLVDDLVNAKTDEVIVKAGTLLDEPMVKAIEEAEVQVARIRSPLVCEADQGVCATCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQLNETSHLESISDGKVEYRDMPTITDKKGRILSLARNGELAVIDAEGREREIHKVPYGTVLMHKDGAKVKEGDRLAEWDPFSLPIITEQSGVVKYQDLIEGTTLEEQTDDATGIAQRVVTENRATGRKKKEDLRPRLTLLSEGQSEDETEAQRYLLAPGTTLSVTDGQTVEAGDILARASREAAKTRDITGGLPRVAELFEARVPKDNAVIAKISGKIEFVREYKAKRKIAIVPEEGEAVDYLIPKTKVIDVQEGDFVKKGDTLISGSPNPHDILDVLGVEALAEYLCTEIQEVYRLQGVKINDKHIEVIVRQMLQKVEITDGGDTVLLPGEQVDRDEMDEANAKLGRGKKPATGNPVLLGITKASLQTRSFISAASFQETTRVLTQASVEGKKDTLIGLKENVIVGRLIPAGTGAGMNRMRVTASARDAALRAQWKKQQEKLAAADEAAMAAEKEPEAEVMDADAMAAAMGGDSAGGDTKPEAPEASEE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000157
EMBL· GenBank· DDBJ
ABC64986.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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