Q2LWX9 · THIM_SYNAS

Function

function

Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; thiamine diphosphate biosynthesis; 4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site47substrate
Binding site123ATP (UniProtKB | ChEBI)
Binding site170ATP (UniProtKB | ChEBI)
Binding site197substrate

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionhydroxyethylthiazole kinase activity
Molecular Functionmagnesium ion binding
Biological Processphosphorylation
Biological Processthiamine biosynthetic process
Biological Processthiamine diphosphate biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Hydroxyethylthiazole kinase
  • EC number
  • Alternative names
    • 4-methyl-5-beta-hydroxyethylthiazole kinase
      (TH kinase
      ; Thz kinase
      )

Gene names

    • Name
      thiM
    • ORF names
      SYN_00303
    • Ordered locus names
      SYNAS_27070

Organism names

Accessions

  • Primary accession
    Q2LWX9

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003365741-270Hydroxyethylthiazole kinase

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the Thz kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    270
  • Mass (Da)
    28,368
  • Last updated
    2006-02-21 v1
  • MD5 Checksum
    7ED47361A9BE1DBC7FEBEBD655B7BB96
MQITPENTWAAVKAIRSRAPLIHNITNYVVMNSTANALLALGASPVMAHAQEEVEEMVGIAQALVVNIGTLSPSWVRAMASAALKAADRGIPIILDPVGAGATAYRTRTAFQLLETVSPTIIRGNASEILAFESVETMETRGVDSTELSQNAVDAGRRLNDSYGSTVCISGETDFIIGDRAILGIRNGHPLMTRVTGLGCTASALCGAFAAVNSSFTLAAAQAMAVMGIAGEMAAEISPGPGSLQLHFLDILYRLTEEDIARRLRIVAGE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000252
EMBL· GenBank· DDBJ
ABC78586.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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