Q2LVL5 · LPXD_SYNAS

Function

function

Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

Catalytic activity

Pathway

Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.

Features

Showing features for active site.

136350100150200250300350
TypeIDPosition(s)Description
Active site239Proton acceptor

GO annotations

AspectTerm
Molecular FunctionN-acyltransferase activity
Biological Processlipid A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    UDP-3-O-acylglucosamine N-acyltransferase
  • EC number

Gene names

    • Name
      lpxD
    • ORF names
      SYN_01568
    • Ordered locus names
      SYNAS_22480

Organism names

Accessions

  • Primary accession
    Q2LVL5

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002644491-363UDP-3-O-acylglucosamine N-acyltransferase

Interaction

Subunit

Homotrimer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region342-363Disordered

Sequence similarities

Belongs to the transferase hexapeptide repeat family. LpxD subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    363
  • Mass (Da)
    38,941
  • Last updated
    2006-02-21 v1
  • Checksum
    A70BEB6CFDD81FF2
MKKSINEIADFLGGKVVGDGGILIKAVRGIDEAGPGDITFVANPQYEKKLNETGASAVLVTRDTERPGENVTLIQVDDPYVSLGKLLTIFYPEEREKPGISAQAIVEEGAEISPSATVYPGVYISSGAGIGAGVVLYPGVFVGRDAVIGENSILYPNVCVYRRCLIGKRVILHAGAVVGSDGFGFANPGRDNIKIPQIGIVQIDDDVEIGANTTIDRATLGRTWIQRGVKIDNLVQIAHNVVIGEKSIIVSQVGISGSTRLGRSVILGGQAGLVGHLQIGDFAMVGAQSGVHEDVPANSVVSGSPCQPHRNWLRSMSCLPRLPDMRHLLNDLRKRIETLEKLSEMKKEVEKEKESSREKEETK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000252
EMBL· GenBank· DDBJ
ABC78127.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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