Q2LR65 · CHEB1_SYNAS

Function

function

Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.

Catalytic activity

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site170
Active site197
Active site290

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionphosphorelay response regulator activity
Molecular Functionprotein-glutamate methylesterase activity
Molecular Functionprotein-glutamine glutaminase activity
Biological Processchemotaxis
Biological Processprotein deamination
Biological Processprotein demethylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein-glutamate methylesterase/protein-glutamine glutaminase 1
  • EC number

Gene names

    • Name
      cheB1
    • ORF names
      SYN_00430
    • Ordered locus names
      SYNAS_06930

Organism names

Accessions

  • Primary accession
    Q2LR65

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_00002643281-350Protein-glutamate methylesterase/protein-glutamine glutaminase 1
Modified residue544-aspartylphosphate

Post-translational modification

Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

Keywords

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-121Response regulatory
Domain148-342CheB-type methylesterase

Domain

Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.

Sequence similarities

Belongs to the CheB family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    350
  • Mass (Da)
    37,995
  • Last updated
    2006-12-12 v2
  • MD5 Checksum
    4CFD5A8A7FAB59B3A17CD37470F4FDE0
MIKVLIVEDSPVVRELLSHILHSDPQIRVVGVAESGEEALKEVVRLRPDLITMDVNLPRMDGFETTRRIMEEIPTPIIIVSAAWVSTEVEKTFRALEAGALAVLEKPSIAARDYDIRARDLIRAVKAMSEVKVIRRWSRSPRIEPAPPASGEPDIGKITKRFEVVAMGASTGGPTVLKQILSDLPDNFTIPILIVQHMTQGFIPGFVDWLSRAANYPVSVAVHGEEIRPGHAYVAPDGLHMGVNALGKIILTKGEPENGLCPSVSYLFRSVYRAYGENAVGVLLTGMGKDGAYELKVMKDCGMITIAQNKETSVVYGMPGEAIGMNAASYVLPPEKIARVLVKLAGSVAP

Sequence caution

The sequence ABC76572.1 differs from that shown. Reason: Erroneous initiation

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP000252
EMBL· GenBank· DDBJ
ABC76572.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation

Genome annotation databases

Similar Proteins

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