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Q2LEZ0 · Q2LEZ0_BOVIN

  • Protein
    Forkhead/winged helix transcription factor 3
  • Gene
    Foxp3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    3/5

Function

Features

Showing features for dna binding.

143150100150200250300350400
TypeIDPosition(s)Description
DNA binding337-423Fork-head

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnucleus
Molecular FunctionDNA-binding transcription factor activity
Molecular Functionmetal ion binding
Molecular FunctionNFAT protein binding
Molecular Functionprotein homodimerization activity
Molecular Functionsequence-specific DNA binding
Biological Processnegative regulation of cell population proliferation
Biological Processnegative regulation of CREB transcription factor activity
Biological Processnegative regulation of cytokine production
Biological Processnegative regulation of DNA-binding transcription factor activity
Biological Processnegative regulation of DNA-templated transcription
Biological Processnegative regulation of immune response
Biological Processnegative regulation of interleukin-10 production
Biological Processnegative regulation of interleukin-2 production
Biological Processnegative regulation of interleukin-4 production
Biological Processnegative regulation of NF-kappaB transcription factor activity
Biological Processnegative regulation of T cell cytokine production
Biological Processnegative regulation of T cell proliferation
Biological Processnegative regulation of type II interferon production
Biological Processpositive regulation of DNA-templated transcription
Biological ProcessT cell activation

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Forkhead/winged helix transcription factor 3

Gene names

    • Name
      Foxp3

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Bovidae > Bovinae > Bos

Accessions

  • Primary accession
    Q2LEZ0

Subcellular Location

Keywords

  • Cellular component

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-70Disordered
Compositional bias36-67Polar residues
Domain337-423Fork-head

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    431
  • Mass (Da)
    47,418
  • Last updated
    2006-02-21 v1
  • MD5 Checksum
    FC7D5A2D2F2F0BFD65DE3DD07CDC7870
MPNPRPAKPLAPSLVLSPSPGASPSWRAAPKASDQLGTKSPGTTFQGRDLRSGAHTSSSSLNPMPPSQLQMPTVPLVMVAPSGARLGPSPHLQALLQDRPHFVHQLSTVDAHARTPVLQVRPLDSPAMISLPPPTAATGLFSLKARPGLPPGINVASLEWVSREPALLCTFPSPGMPRKDSTLSTVPQGSYSLLANGVCKWPGCEKVFKEPEDFLKHCQADHLLDEKGRAQCLLQREVVQSLEQQLVLEKEKLGAMQAHLAGKMAQTKAPSAASSDKGSCCIVATGTPGTTVPAWPGPQEAPDGLFAVRRHLWGSHGNSTFPEFFHNMDYFKFHNMRPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVESEKGVVWTVDEFEFRKKRSQRPSRCSNPTPGP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias36-67Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
DQ322170
EMBL· GenBank· DDBJ
ABC59848.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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